CAS 4101-30-8

2'-Amino-4',5'-dimethoxyacetophenone

Description:

2'-Amino-4',5'-dimethoxyacetophenone, with the CAS number 4101-30-8, is an organic compound characterized by its acetophenone structure, which includes an amino group and two methoxy groups. This compound typically appears as a solid and is soluble in organic solvents, reflecting its moderate polarity due to the presence of both hydrophobic (methoxy) and hydrophilic (amino) functional groups. The amino group can participate in hydrogen bonding, influencing its reactivity and interactions in various chemical environments. The methoxy groups enhance the electron-donating properties of the molecule, potentially affecting its reactivity in electrophilic aromatic substitution reactions. This compound may be of interest in synthetic organic chemistry and medicinal chemistry, as derivatives of acetophenone are often explored for their biological activities. Additionally, its structural features suggest potential applications in the development of pharmaceuticals or agrochemicals, although specific applications would depend on further research into its biological properties and reactivity.

Formula: C₁₀H₁₃NO₃

InChI: InChI=1/C10H13NO3/c1-6(12)7-4-9(13-2)10(14-3)5-8(7)11/h4-5H,11H2,1-3H3

SMILES: CC(=O)c1cc(c(cc1N)OC)OC

Synonyms:

• Ethanone, 1-(2-amino-4,5-dimethoxyphenyl)-
• 1-(2-Amino-4,5-dimethoxyphenyl)ethanone
• 2-Amino-4,5-dimethoxyacetophenone
• 2'-Amino-4',5'-dimethoxyacetophenone
• 2'-AMINO-4',5'-DIMETHOXYACETOPHENONE
• 1-(2-AMINO-4,5-DIMETHOXYHENYL) ETHANONE
• LABOTEST-BB LT00080708
• 1-(2-AMINO-4,5-DIMETHOXY-PHENYL)-ETHANONE

2'-Amino-4',5'-dimethoxyacetophenone, 98%

CAS: 4101-30-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₃NO₃

Purity: 98%

Color and Shape: Yellow, Powder

Molecular weight: 195.22

Ref: 02-L10605

2-Amino-4,5-Dimethoxyacetophenone

CAS: 4101-30-8

Formula: C₁₀H₁₃NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 195.2151

Ref: IN-DA003GEF

2'-Amino-4',5'-dimethoxyacetophenone

CAS: 4101-30-8

2'-Amino-4',5'-dimethoxyacetophenone

Purity: 98%

Molecular weight: 195.22g/mol

Ref: 54-OR927720

2'-Amino-4',5'-dimethoxyacetophenone

CAS: 4101-30-8

2'-Amino-4',5'-dimethoxyacetophenone (2-ADMA) is a topoisomerase inhibitor. 2-ADMA inhibits the growth of cancer cells by targeting the epidermal growth factor receptor (EGFR), which is the major signaling pathway for cell division and survival. It has been shown to inhibit EGFR in a number of cancers, including breast and prostate cancer. 2-ADMA binds to the iminium group on the receptor and prevents binding of EGF ligands, preventing downstream signal transduction. This drug also has pharmacophore properties that are similar to lapatinib, a drug used for the treatment of breast cancer.

Formula: C₁₀H₁₃NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 195.22 g/mol

Ref: 3D-FA70489

1-(2-Amino-4,5-dimethoxy-phenyl)-ethanone

CAS: 4101-30-8

Formula: C₁₀H₁₃NO₃

Purity: 95%

Color and Shape: Yellow or pale brown powder

Molecular weight: 195.218

Ref: 10-F031691