CAS 41020-65-9

Pregn-4-ene-7,21-dicarboxylic acid, 17-hydroxy-3-oxo-, γ-lactone, 7-methyl ester, (7α,17α)-

Description:

Pregn-4-ene-7,21-dicarboxylic acid, 17-hydroxy-3-oxo-, γ-lactone, 7-methyl ester, (7α,17α)-, commonly referred to as a derivative of steroid compounds, exhibits several notable characteristics. This compound features a steroid backbone, which is characterized by a four-ring carbon structure. The presence of multiple functional groups, including carboxylic acid and ester moieties, contributes to its chemical reactivity and potential biological activity. The γ-lactone structure indicates a cyclic ester formation, which can influence the compound's solubility and stability. Additionally, the specific stereochemistry denoted by (7α,17α)- suggests that the compound has defined spatial arrangements of its atoms, which can significantly affect its interaction with biological targets, such as receptors or enzymes. This compound may be of interest in pharmaceutical research, particularly in the development of steroid-based therapeutics. Its CAS number, 41020-65-9, allows for precise identification in chemical databases and literature. Overall, this compound exemplifies the complexity and diversity of steroid derivatives in medicinal chemistry.

Formula: C₂₄H₃₂O₅

InChI: InChI=1/C24H32O5/c1-23-11-9-19-21(18(23)6-4-14(23)5-7-20(26)27)17(22(28)29-3)13-15-12-16(25)8-10-24(15,19)2/h8,10,12,14,17-19,21H,4-7,9,11,13H2,1-3H3,(H,26,27)/t14?,17-,18+,19+,21+,23-,24+/m1/s1

InChI key: InChIKey=ADZYJDJNIBFOQE-RGKMBJPFSA-N

SMILES: C[C@@]12[C@]3(CC[C@]1([C@]4([C@](CC2)([C@]5(C)C(C[C@H]4C(OC)=O)=CC(=O)CC5)[H])[H])[H])OC(=O)CC3

Synonyms:

• 17-Hydroxy-3-oxo-17α-pregn-4-ene-7α,21-dicarboxylic acid methyl ester γ-lactone
• Spiro[17H-cyclopenta[a]phenanthrene-17,2′(5′H)-furan], pregn-4-ene-7,21-dicarboxylic acid deriv.
• Pregn-4-ene-7,21-dicarboxylic acid, 17-hydroxy-3-oxo-, γ-lactone, 7-methyl ester, (7α,17α)-
• Pregn-4-ene-7,21-dicarboxylic acid, 17-hydroxy-3-oxo-, γ-lactone, methyl ester, (7α,17α)-
• 17-Hydroxy-7α-(methoxycarbonyl)-3-oxo-17α-pregn-4-ene-21-carboxylic acid lactone
• (2''R)-3'',4''-dihydro-7α-methoxycarbonylspiro[androst-4-ene-17,2''-furan]-3,5''-dione
• Eplerenone EP Impurity G
• Eplerenone 9,11-Dihydro Impurity
• (2\'R,7R,8R,9S,10R,13S,14S)-methyl 10,13-dimethyl-3,5\'-dioxo-1,2,3,4\',5\',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3\'H-spiro[cyclopenta[a]phenanthrene-17,2\'-furan]-7-carboxylate
• Eplerenone Impurity G
• Eplerenone Impurity 16(Eplerenone EP Impurity G)
• SC 25152
• Eplerenone EP Imp G
• Mexrenone

Eplerenone EP Impurity G

CAS: 41020-65-9

Formula: C₂₄H₃₂O₅

Color and Shape: White To Off-White Solid

Molecular weight: 400.52

Ref: 4Z-E-1314

Mexrenone

Controlled Product

CAS: 41020-65-9

Applications Mexrenone is an impurity of eplerenon (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),

Formula: C₂₄H₃₂O₅

Color and Shape: Off-White

Molecular weight: 400.5079

Ref: TR-M340840

Eplerenone EP Impurity G

CAS: 41020-65-9

Formula: C₂₄H₃₂O₅

Molecular weight: 400.52

Ref: ST-EA-CP-E37007