CAS 4105-38-8

2′,3′,5′-Tri-O-acetyluridine

Description:

2′,3′,5′-Tri-O-acetyluridine is a modified nucleoside derivative of uridine, characterized by the presence of three acetyl groups attached to the hydroxyl groups at the 2′, 3′, and 5′ positions of the ribose sugar. This modification enhances the lipophilicity of the molecule, which can influence its biological activity and stability. The compound is typically a white to off-white solid and is soluble in organic solvents such as methanol and chloroform, but less soluble in water due to the acetyl groups. It is often used in biochemical research and synthetic chemistry, particularly in the study of nucleic acids and as a building block for oligonucleotide synthesis. The acetylation of uridine can affect its interactions with enzymes and receptors, making it a valuable tool in the exploration of nucleoside function and metabolism. As with many chemical substances, proper handling and storage conditions are essential to maintain its integrity and prevent degradation.

Formula: C₁₅H₁₈N₂O₉

InChI: InChI=1S/C15H18N2O9/c1-7(18)23-6-10-12(24-8(2)19)13(25-9(3)20)14(26-10)17-5-4-11(21)16-15(17)22/h4-5,10,12-14H,6H2,1-3H3,(H,16,21,22)/t10-,12-,13-,14-/m1/s1

InChI key: InChIKey=AUFUWRKPQLGTGF-FMKGYKFTSA-N

SMILES: O(C(C)=O)[C@H]1[C@@H](O[C@H](COC(C)=O)[C@H]1OC(C)=O)N2C(=O)NC(=O)C=C2

Synonyms:

• 1-(2,3,5-tri-O-acetylpentofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 2',3',5'-Triacetyluridine
• 2',3',5'-tri-O-acetyluridine
• 2′,3′,5′-Tri-O-acetyluridine
• Chembridge 5106522
• Pn 401
• Rg 2133
• Tri-O-acetyl uridine
• Triacetyluridine
• Uridine triacetate
• Uridine, 2′,3′,5′-triacetate
• Vistogard
• Vistonuridine
• Xuriden

2',3',5'-Tri-O-acetyluridine

CAS: 4105-38-8

Formula: C₁₅H₁₈N₂O₉

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 370.31

Ref: 3B-T2549

2',3',5'-Tri-O-acetyluridine

CAS: 4105-38-8

Formula: C₁₅H₁₈N₂O₉

Purity: 97%

Color and Shape: Solid

Molecular weight: 370.3114

Ref: IN-DA003FFK

Uridine triacetate

CAS: 4105-38-8

Uridine triacetate

Purity: ≥98%

Molecular weight: 370.31g/mol

Ref: 54-BUP17071

2',3',5'-Tri-O-acetyluridine

CAS: 4105-38-8

2',3',5'-Tri-O-acetyluridine

Purity: 98%

Molecular weight: 370.31g/mol

Ref: 54-OR1009966

Uridine triacetate

CAS: 4105-38-8

Uridine triacetate, an oral prodrug of Uridine, is used to research 5-FU and capecitabine toxicity.

Formula: C₁₅H₁₈N₂O₉

Purity: 99.89%

Color and Shape: White Or Almost White Crystalline Powder

Molecular weight: 370.31

Ref: TM-T21327

2'',3'',5''-Triacetyluridine

CAS: 4105-38-8

Formula: C₁₅H₁₈N₂O₉

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 370.31

Ref: 7W-GE4701

2',3',5'-Tri-O-acetyluridine

CAS: 4105-38-8

2',3',5'-Tri-O-acetyluridine is a uridine derivative with potential for use in organic synthesis such as the preparation of modified nucleosides, nucleotides, and RNA analogs.

Formula: C₁₅H₁₈N₂O₉

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 370.31 g/mol

Ref: 3D-NT06907

Uridine triacetate

CAS: 4105-38-8

Purity: 98%

Molecular weight: 370.101

Ref: 10-F788439

2’,3’,5’-Triacetyluridine

Controlled Product

CAS: 4105-38-8

Applications 2’,3’,5’-Triacetyluridine is used in the treatment of Alzheimer’s disease in mice and provide neuroprotective effects. Shown to also decrease depressive symptoms and increases in brain pH bipolar patients.
References Saydoff, J. et al.: J. Alzheimers Dis., 36, 637 (2013); Jensen, J. et al.: Exp. Clin. Psychopharm., 16, 199 (2008);

Formula: C₁₅H₁₈N₂O₉

Color and Shape: Neat

Molecular weight: 370.311

Ref: TR-T767025