CAS 41092-64-2

inosine 3':5'-cyclic monophosphate*sodium

Description:

Inosine 3',5'-cyclic monophosphate sodium (commonly referred to as sodium cyclic inosinate or cIMP) is a nucleotide derivative that plays a significant role in cellular signaling processes. It is characterized by its cyclic structure, which includes a ribose sugar, a phosphate group, and an inosine base. The cyclic monophosphate form is crucial in various biological functions, particularly in the regulation of intracellular signaling pathways, including those involving protein kinases and phosphodiesterases. As a sodium salt, it is soluble in water, making it suitable for various biochemical applications. cIMP is involved in the modulation of physiological responses, such as vasodilation and neurotransmission, and serves as a secondary messenger in signal transduction. Its stability and reactivity can be influenced by environmental factors such as pH and temperature. Overall, inosine 3',5'-cyclic monophosphate sodium is an important compound in biochemistry and pharmacology, with potential implications in therapeutic research and development.

Formula: C₁₀H₁₁N₄NaO₇P

InChI: InChI=1/C10H11N4O7P.Na/c15-6-7-4(1-19-22(17,18)21-7)20-10(6)14-3-13-5-8(14)11-2-12-9(5)16;/h2-4,6-7,10,15H,1H2,(H,17,18)(H,11,12,16);

SMILES: C1C2C(C(C(n3cnc4c3ncnc4O)O2)O)OP(=O)(O)O1.[Na]

Synonyms:

• 6H-purin-6-one, 3,9-dihydro-9-(tetrahydro-2,7-dihydroxy-2-oxido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl)-, monosodium salt

Inosine 3′:5′-cyclic monophosphate sodium salt

CAS: 41092-64-2

Formula: C₁₀H₁₀N₄O₇PNa

Molecular weight: 352.17

Ref: 7W-GL9458

Inosine-3',5'-cyclic Monophosphate Sodium Salt

Controlled Product

CAS: 41092-64-2

Applications Inosine-3',5'-cyclic monophosphate is a cyclic nucleotide that stimulates steroidogenesis by adrenocortical cells in rats. Inosine-3',5'-cyclic monophosphate also stimulates insulin secretion in hamster pancreas cells.
References Cooper, R., et al.: Biochem. J., 127, 143 (1972); Feldman, J. & Jackson, T.: Endocrinology, 94, 388 (1974); Nussdorfer, G., et al.: Endocrinology, 92, 141 (1973)

Formula: C₁₀H₁₀N₄O₇P·Na

Color and Shape: Neat

Molecular weight: 352.17

Ref: TR-I661100

(inosine-3',5'-cyclic-13C5) Monophosphate Sodium Salt

Controlled Product

CAS: 41092-64-2

Formula: C₅₁₃C₅H₁₀N₄NaO₇P

Color and Shape: Neat

Molecular weight: 353.104

Ref: TR-I661102

Inosine-3',5'-cyclic-monophosphate sodium

CAS: 41092-64-2

Inosine-3',5'-cyclic-monophosphate sodium (cIMP) is a metabolite of inosine and is generated by the enzyme inosine monophosphate cyclohydrolase. cIMP has been shown to be related to colorectal adenocarcinoma, cancer, and body mass index. It has also been implicated in the diagnosis of cancer and infectious diseases. cIMP is involved in energy metabolism and DNA synthesis, which are important for the progression of renal cell cancer. In addition, it has been shown that cIMP can function as a biomarker for prognosis when used with multivariate logistic regression.

Formula: C₁₀H₁₁N₄O₇P·Na

Purity: Min. 95%

Molecular weight: 353.18 g/mol

Ref: 3D-NI170529