CAS 41100-52-1: Memantine hydrochloride

Description: Memantine hydrochloride is a pharmaceutical compound primarily used in the treatment of Alzheimer's disease and other forms of dementia. It acts as an N-methyl-D-aspartate (NMDA) receptor antagonist, which helps to regulate glutamate activity in the brain, thereby potentially improving cognitive function and slowing disease progression. The substance is typically presented as a white to off-white crystalline powder, soluble in water, and has a relatively low molecular weight. Memantine hydrochloride has a pKa value indicating its weak basic nature, which influences its absorption and distribution in the body. The compound is administered orally, often in the form of tablets or solution, and its pharmacokinetics show a moderate half-life, allowing for once or twice daily dosing. Side effects may include dizziness, headache, and constipation, but it is generally well-tolerated. As with any medication, it is essential to use memantine hydrochloride under medical supervision to monitor efficacy and manage any potential adverse effects.

Formula: C₁₂H₂₁N·ClH

InChI: InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H

InChI key: InChIKey=LDDHMLJTFXJGPI-UHFFFAOYSA-N

SMILES: Cl.NC12CC3CC(C)(C1)CC(C)(C3)C2

Synonyms:

• 1,3-Dimethyl-5-Aminoadamantane Hydrochloride
• 1,3-Dimethylaminoadamantane Hydrochloride
• 1-Adamantanamine, 3,5-dimethyl-, hydrochloride
• 1-Amino-3,5-Dimethyladamantane Hcl
• 1-Amino-3,5-dimethyladamantane hydrochloride
• 3,5-Dimethyl-1-Aminoadamantane Hydrochloride
• 3,5-Dimethyl-adamantan-1-ylamine; hydrochloride
• 3,5-Dimethyladamantan-1-Amine HCl
• 3,5-Dimethyladamantan-1-amine hydrochloride
• 3,5-Dimethyladamantanamine Hydrochloride
• 3,5-Dimethyltricyclo[3.3.1.1^3,7]decan-1-amine hydrochloride
• 3,5-Dimethyltricyclo[3.3.1.1~3,7~]Decan-1-Amine Hydrochloride (1:1)
• 3.5-Dimethyl-1-Aminoadamantane Hydrochloride
• Akatinol
• Axura
• D-145
• Dmaa
• Ebixa
• Ebixia
• Ebixza
• Labotest-Bb Lt00233220
• Mantine
• Marixino
• Memantine Hcl
• Memantine Hydrochloride
• Memantine LEK
• Memary
• NSC 102290
• Namenda
• Sun Y7017
• Tricyclo[3.3.1.1^3,7]decan-1-amine, 3,5-dimethyl-, hydrochloride
• Tricyclo[3.3.1.1^3,7]decan-1-amine, 3,5-dimethyl-, hydrochloride (1:1)
• Tricyclo[3.3.1.13,7]decan-1-amine, 3,5-dimethyl-, hydrochloride
• Tricyclo[3.3.1.13,7]decan-1-amine, 3,5-dimethyl-, hydrochloride (1:1)

Memantine hydrochloride

CAS: 41100-52-1

An NMDA receptor antagonist; stimulates dopamine release This Thermo Scientific Chemicals brand product was originally …

• Formula: C₁₂H₂₂ClN
• Color and Shape: White to off-white, Solid
• Molecular weight: 215.77

Memantine hydrochloride CRS

CAS: 41100-52-1

Memantine Hydrochloride

CAS: 41100-52-1

Cyclanic, cyclenic or cycloterpenic mono- or polyamines, and their derivatives; salts thereof

• Formula: C₁₂H₂₁N·ClH
• Color and Shape: Off-White Powder
• Molecular weight: 215.14408

Memantine hydrochloride

CAS: 41100-52-1

Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects.

• Formula: C₁₂H₂₂ClN
• Purity: 99.56% - 99.96%
• Color and Shape: Crystalline Solid
• Molecular weight: 215.763

Tricyclo[3.3.1.13,7]decan-1-amine, 3,5-dimethyl-, hydrochloride

CAS: 41100-52-1

• Formula: C₁₂H₂₂ClN
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 215.7627800000001

Memantine Hydrochloride

CAS: 41100-52-1

• Molecular weight: 215.76g/mol

Memantine hydrochloride

CAS: 41100-52-1

• Purity: 99.56%
• Molecular weight: 215.763g/mol

Memantine hydrochloride

CAS: 41100-52-1

• Formula: C₁₂H₂₁N·HCl
• Purity: (Titration) ≥ 98.0% (dried basis)
• Color and Shape: White or almost white powder
• Molecular weight: 215.76

Memantine HCl

CAS: 41100-52-1

• Formula: C₁₂H₂₁N·HCl
• Color and Shape: White To Off-White Solid
• Molecular weight: 179.31 36.46

1-Amino-3,5-dimethyl-d6-adamentane-2,2,7,8,8,9,9-d7HCl

CAS: 41100-52-1

• Purity: 99 atom % D (also 61% deuterated at positions C-6 and C-10 as well as 14% deuterated at position C-4)
• Molecular weight: 227.84

3,5-Dimethyl-1-adamantanamine Hydrochloride

CAS: 19982-08-2 41100-52-1

• Formula: C₁₂H₂₁N·HCl
• Purity: >98.0%(T)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 215.77

Memantine hydrochloride

CAS: 41100-52-1

• Formula: C₁₂H₂₁N·ClH
• Color and Shape: Neat
• Molecular weight: 215.76

Memantine Hydrochloride

CAS: 41100-52-1

• Formula: C₁₂H₂₁N·ClH
• Color and Shape: Neat
• Molecular weight: 215.76

1,3-Dimethyl-5-aminoadamantane hydrochloride, 95%

CAS: 41100-52-1

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₂H₂₂ClN
• Purity: 95%
• Molecular weight: 215.77

Memantine Hydrochloride

CAS: 41100-52-1

Stability Hygroscopic Applications Used as an antiparkinsonian and antispasmodic. References Rohde, H., et al.: Fortschr. …

• Formula: C₁₂H₂₁N·ClH
• Color and Shape: White To Off-White
• Molecular weight: 215.76

Memantine HCl

CAS: 41100-52-1

NMDA receptor antagonist

• Formula: C₁₂H₂₁N·HCl
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 215.77 g/mol

Memantine hydrochloride - Bio-X ™

CAS: 41100-52-1

Memantine is an NMDA receptor antagonist that is an effective therapeutic agent for Alzheimer’s disease …

• Formula: C₁₂H₂₁N·HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 215.76 g/mol