CAS 41100-52-1

Memantine hydrochloride

Description:

Memantine hydrochloride is a pharmaceutical compound primarily used in the treatment of Alzheimer's disease and other forms of dementia. It acts as an N-methyl-D-aspartate (NMDA) receptor antagonist, which helps to regulate glutamate activity in the brain, thereby potentially improving cognitive function and slowing disease progression. The substance is typically presented as a white to off-white crystalline powder, soluble in water, and has a relatively low molecular weight. Memantine hydrochloride has a pKa value indicating its weak basic nature, which influences its absorption and distribution in the body. The compound is administered orally, often in the form of tablets or solution, and its pharmacokinetics show a moderate half-life, allowing for once or twice daily dosing. Side effects may include dizziness, headache, and constipation, but it is generally well-tolerated. As with any medication, it is essential to use memantine hydrochloride under medical supervision to monitor efficacy and manage any potential adverse effects.

Formula: C₁₂H₂₁N·ClH

InChI: InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H

InChI key: InChIKey=LDDHMLJTFXJGPI-UHFFFAOYSA-N

SMILES: CC12CC3(C)CC(N)(C1)CC(C2)C3.Cl

Synonyms:

• 1,3-Dimethyl-5-Aminoadamantane Hydrochloride
• 1,3-Dimethylaminoadamantane Hydrochloride
• 1-Adamantanamine, 3,5-dimethyl-, hydrochloride
• 1-Amino-3,5-Dimethyladamantane Hcl
• 1-Amino-3,5-dimethyladamantane hydrochloride
• 3,5-Dimethyl-1-Aminoadamantane Hydrochloride
• 3,5-Dimethyl-adamantan-1-ylamine; hydrochloride
• 3,5-Dimethyladamantan-1-Amine HCl
• 3,5-Dimethyladamantan-1-amine hydrochloride
• 3,5-Dimethyladamantanamine Hydrochloride
• 3,5-Dimethyltricyclo[3.3.1.1^3,7]decan-1-amine hydrochloride
• 3,5-Dimethyltricyclo[3.3.1.1~3,7~]Decan-1-Amine Hydrochloride (1:1)
• 3.5-Dimethyl-1-Aminoadamantane Hydrochloride
• Akatinol
• Axura
• D-145
• Dmaa
• Ebixa
• Ebixia
• Ebixza
• Labotest-Bb Lt00233220
• Mantine
• Marixino
• Memantine Hcl
• Memantine Hydrochloride
• Memantine LEK
• Memary
• NSC 102290
• Namenda
• Sun Y7017
• Tricyclo[3.3.1.1^3,7]decan-1-amine, 3,5-dimethyl-, hydrochloride
• Tricyclo[3.3.1.1^3,7]decan-1-amine, 3,5-dimethyl-, hydrochloride (1:1)
• Tricyclo[3.3.1.13,7]decan-1-amine, 3,5-dimethyl-, hydrochloride

Memantine hydrochloride

CAS: 41100-52-1

An NMDA receptor antagonist; stimulates dopamine release

Formula: C₁₂H₂₂ClN

Color and Shape: White to off-white, Solid

Molecular weight: 215.77

Ref: 02-J63830

MEMANTINE HYDROCHLORIDE CRS

CAS: 41100-52-1

MEMANTINE HYDROCHLORIDE CRS

Ref: 41-Y0002489

Memantine Hydrochloride

CAS: 41100-52-1

Cyclanic, cyclenic or cycloterpenic mono- or polyamines, and their derivatives; salts thereof

Formula: C₁₂H₂₁N·ClH

Color and Shape: Off-White Powder

Molecular weight: 215.14408

Ref: 45-1380502

Tricyclo[3.3.1.13,​7]​decan-​1-​amine, 3,​5-​dimethyl-​, hydrochloride (1:1)

CAS: 41100-52-1

Formula: C₁₂H₂₂ClN

Purity: 98%

Color and Shape: Solid

Molecular weight: 215.7628

Ref: IN-DA00I81R

Memantine hydrochloride

CAS: 41100-52-1

Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects.

Formula: C₁₂H₂₂ClN

Purity: 99.56% - 99.96%

Color and Shape: Crystalline Solid

Molecular weight: 215.76

Ref: TM-T1443

Memantine HCl

CAS: 41100-52-1

Formula: C₁₂H₂₁N·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 179.31 36.46

Ref: 4Z-M-381

Memantine hydrochloride

CAS: 41100-52-1

Formula: C₁₂H₂₁N·HCl

Purity: (Titration) ≥ 98.0% (dried basis)

Color and Shape: White or almost white powder

Molecular weight: 215.76

Ref: 7W-GP8214

Memantine Hydrochloride

CAS: 41100-52-1

Memantine Hydrochloride

Purity: 98%

Molecular weight: 215.76g/mol

Ref: 54-OR1030261

Memantine hydrochloride

CAS: 41100-52-1

Memantine hydrochloride

Purity: ≥98%

Molecular weight: 215.763g/mol

Ref: 54-BUP17884

1-Amino-3,5-dimethyl-d6-adamentane-2,2,7,8,8,9,9-d7HCl

CAS: 41100-52-1

Purity: 99 atom % D (also 61% deuterated at positions C-6 and C-10 as well as 14% deuterated at position C-4)

Molecular weight: 227.84

Ref: 3U-D8027

Memantine hydrochloride

Controlled Product

CAS: 41100-52-1

Formula: C₁₂H₂₁N·ClH

Color and Shape: Neat

Molecular weight: 215.76

Ref: 04-C14862700

3,5-Dimethyl-1-adamantanamine Hydrochloride

CAS: 19982-08-2, 41100-52-1

Formula: C₁₂H₂₁N·HCl

Purity: >98.0%(T)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 215.77

Ref: 3B-D3608

Memantine Hydrochloride

CAS: 41100-52-1

Formula: C₁₂H₂₁N·ClH

Color and Shape: Neat

Molecular weight: 215.76

Ref: 86-MM1045.00

Memantine Hydrochloride

Controlled Product

CAS: 41100-52-1

Stability Hygroscopic
Applications Used as an antiparkinsonian and antispasmodic.
References Rohde, H., et al.: Fortschr. Med., 100, 2023 (1982), Kornhuber, J., et al.: Eur. J. Pharmacol., 166, 589 (1989), Gortelmeyer, R. and Erbler, H.: Arzneimittel-Forsch., 42, 904 (1992)

Formula: C₁₂H₂₁N·ClH

Color and Shape: White To Off-White

Molecular weight: 215.76

Ref: TR-M218000

Memantine HCl

Controlled Product

CAS: 41100-52-1

NMDA receptor antagonist

Formula: C₁₂H₂₁N·HCl

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 215.77 g/mol

Ref: 3D-FM05692

Memantine hydrochloride - Bio-X ™

Controlled Product

CAS: 41100-52-1

Memantine is an NMDA receptor antagonist that is an effective therapeutic agent for Alzheimer’s disease and other neurodegenerative diseases. This drug inhibits the NDMA receptor preventing glutamate from carrying out its function thus helping with the symptoms associated with Alzheimer’s.

Formula: C₁₂H₂₁N·HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 215.76 g/mol

Ref: 3D-BM164662