CAS 411207-31-3

Tiotropium bromide monohydrate

Description:

Tiotropium bromide monohydrate is a long-acting anticholinergic medication primarily used in the management of chronic obstructive pulmonary disease (COPD) and asthma. It functions by inhibiting the action of acetylcholine on muscarinic receptors in the airways, leading to bronchodilation and improved airflow. This compound is characterized by its high solubility in water, which enhances its bioavailability when administered via inhalation. Tiotropium bromide is typically formulated as a dry powder inhaler or nebulizer solution, allowing for targeted delivery to the lungs. The monohydrate form indicates the presence of one molecule of water associated with each molecule of tiotropium bromide, which can influence its stability and solubility. The substance is generally well-tolerated, with common side effects including dry mouth and throat irritation. Its pharmacokinetic profile allows for once-daily dosing, making it a convenient option for patients. Overall, tiotropium bromide monohydrate plays a crucial role in the therapeutic management of respiratory conditions, improving patients' quality of life.

Formula: C₁₉H₂₂NO₄S₂·Br·H₂O

InChI: InChI=1/C19H22NO4S2.BrH.H2O/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15;;/h3-8,11-13,16-17,22H,9-10H2,1-2H3;1H;1H2/q+1;;/p-1/t11-,12-,13+,16-,17+;;

InChI key: InChIKey=MQLXPRBEAHBZTK-SEINRUQRNA-M

SMILES: C(C(O[C@H]1C[C@]2([C@]3([C@@]([C@@](C1)([N+]2(C)C)[H])(O3)[H])[H])[H])=O)(O)(C4=CC=CS4)C5=CC=CS5.[Br-].O

Synonyms:

• 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-, bromide, monohydrate, (1α,2β,4β,5α,7β)-
• 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-, bromide, hydrate (1:1:1), (1α,2β,4β,5α,7β)-
• Tiotropium bromide monohydrate

Tiotropium Bromide hydrate

CAS: 411207-31-3

Tiotropium Bromide hydrate

Purity: ≥98%

Molecular weight: 490.43g/mol

Ref: 54-BUP13857

Tiotropium bromide monohydrate

CAS: 411207-31-3

Muscarinic antagonist; bronchodilator

Formula: C₁₉H₂₂NO₄S₂•Br•H₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 490.43 g/mol

Ref: 3D-FT32564

Tiotropium Bromide Monohydrate (TioBr) extrapure, 98%

CAS: 411207-31-3

Formula: C₁₉H₂₂BrNO₄S₂·H₂O

Purity: min. 98%

Color and Shape: White to off white to yellow to beige, Crystalline powder, Clear, Colourless to pale yellow

Molecular weight: 490.43

Ref: SR-77082

Tiotropium Bromide Monohydrate

Controlled Product

CAS: 411207-31-3

Formula: C₁₉H₂₂NO₄S₂·Br·H₂O

Color and Shape: Neat

Molecular weight: 490.43

Ref: TR-T444860

Tiotropium Bromide hydrate

CAS: 411207-31-3

Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.

Formula: C₁₉H₂₄BrNO₅S₂

Purity: 98.44% - 99.41%

Color and Shape: Solid

Molecular weight: 490.43

Ref: TM-T6707