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CAS 41136-22-5

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Ceftezole sodium

Description:
Ceftezole sodium is a broad-spectrum cephalosporin antibiotic used primarily for the treatment of various bacterial infections. It is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a range of Gram-positive and Gram-negative bacteria. The compound is typically administered via injection and is soluble in water, which facilitates its use in clinical settings. Ceftezole sodium is known for its stability in the presence of beta-lactamase enzymes, which are produced by some bacteria to confer resistance to other antibiotics. Its pharmacokinetics include rapid distribution in body tissues and fluids, with a relatively short half-life, necessitating multiple doses for sustained therapeutic effect. Common side effects may include gastrointestinal disturbances, allergic reactions, and potential impacts on renal function. As with all antibiotics, it is crucial to use ceftezole sodium judiciously to minimize the risk of developing antibiotic resistance.
Formula:C13H12N8O4S3·Na
InChI:InChI=1S/C13H12N8O4S3.Na/c22-7(1-20-4-14-18-19-20)16-8-10(23)21-9(12(24)25)6(2-26-11(8)21)3-27-13-17-15-5-28-13;/h4-5,8,11H,1-3H2,(H,16,22)(H,24,25);/t8-,11-;/m1./s1
InChI key:InChIKey=LULDFGMJOLSEIH-JHQAJZDGSA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](NC(CN3C=NN=N3)=O)C2=O)(SCC1CSC4=NN=CS4)[H].[Na]
Synonyms:
  • 5-Thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic sodium
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-3-[(1,3,4-thiadiazol-2-ylthio)methyl]-, monosodium salt, (6R-trans)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[[2-(1H-tetrazol-1-yl)acetyl]amino]-3-[(1,3,4-thiadiazol-2-ylthio)methyl]-, sodium salt (1:1), (6R,7R)-
  • Celoslin
  • Sodium 7-[(1H-tetrazol-4-yl)acetyl]-3-(1,3,4-thiadiazol-5-ylthio)cephalosporanate
  • sodium (6S,7R)-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-3-[(1,3,4-thiadiazol-2-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • Ceftezole sodium
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