CAS 4114-84-5

1-Piperazinesulfonamide,4-ethyl-

Description:

1-Piperazinesulfonamide, 4-ethyl- is a chemical compound characterized by its piperazine ring structure, which is a six-membered ring containing two nitrogen atoms. This compound features a sulfonamide functional group, which is known for its antibacterial properties, and an ethyl group attached to the piperazine ring. The presence of the sulfonamide moiety contributes to its potential biological activity, making it of interest in medicinal chemistry. The compound is typically a solid at room temperature and may exhibit solubility in polar solvents due to the presence of the sulfonamide group. Its molecular structure allows for various interactions, including hydrogen bonding, which can influence its reactivity and biological activity. As with many sulfonamides, it may also exhibit properties such as antimicrobial activity, making it relevant in pharmaceutical applications. Safety data and handling precautions should be considered, as with all chemical substances, to ensure proper usage and minimize risks.

Formula: C₆H₁₅N₃O₂S

Synonyms:

• 1-Piperazinesulfonamide,4-ethyl-(7CI,8CI,9CI)

4-Ethylpiperazine-1-sulfonamide

CAS: 4114-84-5

4-Ethylpiperazine-1-sulfonamide is a potent compound that inhibits the production of lipopolysaccharide. This inhibition leads to less inflammation and pain in patients with rheumatoid arthritis and other inflammatory diseases. 4-Ethylpiperazine-1-sulfonamide has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) in human macrophages by blocking the activation of nuclear transcription factor kappa B (NFκB). This compound also binds to the TNF receptor, inhibiting its ability to activate NFκB. 4-Ethylpiperazine-1-sulfonamide also has antiinflammatory activities and can be used for the treatment of chronic inflammatory disorders such as rheumatoid arthritis.

Formula: C₆H₁₅N₃O₂S

Purity: Min. 95%

Molecular weight: 193.27 g/mol

Ref: 3D-EAA11484