CAS 4124-41-8

p-Toluenesulfonic anhydride

Description:

p-Toluenesulfonic anhydride, with the CAS number 4124-41-8, is an organic compound that serves as a versatile reagent in organic synthesis. It is characterized by its anhydride functional group, which is derived from p-toluenesulfonic acid. This compound typically appears as a colorless to pale yellow liquid and has a strong, pungent odor. It is soluble in organic solvents such as dichloromethane and ether but is generally insoluble in water. p-Toluenesulfonic anhydride is known for its ability to activate alcohols and amines for nucleophilic substitution reactions, making it valuable in the synthesis of esters and amides. It is also used in the preparation of sulfonamides and as a coupling agent in various chemical reactions. Due to its reactivity, it should be handled with care, as it can cause irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment, are essential when working with this compound.

Formula: C₁₄H₁₄O₅S₂

InChI: InChI=1S/C14H14O5S2/c1-11-3-7-13(8-4-11)20(15,16)19-21(17,18)14-9-5-12(2)6-10-14/h3-10H,1-2H3

InChI key: InChIKey=PDVFSPNIEOYOQL-UHFFFAOYSA-N

SMILES: S(OS(=O)(=O)C1=CC=C(C)C=C1)(=O)(=O)C2=CC=C(C)C=C2

Synonyms:

• (4-Methylphenyl)sulfonyl 4-methylbenzenesulfonate
• 1,3-Bis(4-methylphenyl)-1,1,3,3-tetraoxo-1λ6,3λ6-dithioxane
• 4-Methylbenzenesulfonic acid anhydride
• 4-Methylbenzenesulfonic anhydride
• 4-Methylphenylsulfonic anhydride
• 4-Toluenesulfonic acid anhydride
• 4-Toluenesulfonic anhydride
• Benzenesulfonic acid, 4-methyl-, 1,1′-anhydride
• Benzenesulfonic acid, 4-methyl-, anhydride
• P-Tolylsulfonyl 4-Methylbenzenesulfonate
• Toluene-4-sulfonic acid ahnydride
• Toluenesulfonic anhydride
• Tosylic anhydride
• p-Toluenesulfonic acid anhydride
• p-Toluenesulfonyl anhydride

p-Toluenesulfonic Anhydride

CAS: 4124-41-8

Formula: C₁₄H₁₄O₅S₂

Purity: >95.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 326.38

Ref: 3B-T1485

p-Toluenesulfonic anhydride, 97%

CAS: 4124-41-8

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Formula: C₁₄H₁₄O₅S₂

Purity: 97%

Color and Shape: White to cream or pale grey to grey, Crystals or powder or crystalline powder and/or chunks

Molecular weight: 326.38

Ref: 02-L00160

p-Toluenesulfonic Anhydride

CAS: 4124-41-8

Formula: C₁₄H₁₄O₅S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 326.3880

Ref: IN-DA0035JE

Toluene-4-sulphonic anhydride

CAS: 4124-41-8

Toluene-4-sulphonic anhydride

Formula: C₁₄H₁₄O₅S₂

Purity: 95%

Color and Shape: off white to grey crystalline solid

Molecular weight: 326.38795g/mol

Ref: 54-OR0751

p-Toluenesulfonic anhydride

CAS: 4124-41-8

Formula: C₁₄H₁₄O₅S₂

Purity: 95.0%

Color and Shape: Solid, Chunks or Crystalline Powder

Molecular weight: 326.38

Ref: 10-F079025

p-Toluenesulfonic anhydride

CAS: 4124-41-8

p-Toluenesulfonic anhydride is a tosylate reagent for the conversion of alcohols to alkyl tosylates. It is used in chemical biology and biochemistry as a protonation agent, which reacts with nucleophilic groups (e.g., hydroxyl) on proteins or other biomolecules. p-Toluenesulfonic anhydride also has been used in the synthesis of organic compounds, such as drugs, pesticides and herbicides. This compound can be used as a catalyst for palladium-catalyzed coupling reactions that are site specific due to its high reactivity and susceptibility to hydrolysis. p-Toluenesulfonic anhydride is not active on aromatic rings because it does not have a nucleophilic group. This compound can be quantified by gravimetric analysis or FTIR spectroscopy.

Formula: C₁₄H₁₄O₅S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 326.39 g/mol

Ref: 3D-FT28875