CAS 41274-09-3

sn-glyceryl 1-P-toluenesulfonate

Description:

Sn-glyceryl 1-P-toluenesulfonate, with the CAS number 41274-09-3, is an organosulfonate compound characterized by the presence of a glyceryl moiety and a toluenesulfonate group. This compound typically exhibits properties associated with both hydrophilicity and lipophilicity due to its dual functional groups, making it useful in various applications, including as a surfactant or emulsifier. It is often utilized in organic synthesis and pharmaceutical formulations, where it can act as a protecting group for hydroxyl functionalities. The presence of the toluenesulfonate group enhances its reactivity, allowing for further chemical modifications. Additionally, this compound may exhibit low toxicity and good solubility in organic solvents, which is advantageous for its use in laboratory settings. As with many sulfonate esters, it may also demonstrate stability under a range of conditions, although specific stability and reactivity can depend on the surrounding environment and the presence of other reagents. Proper handling and storage conditions are recommended to maintain its integrity and effectiveness in applications.

Formula: C₁₀H₁₄O₅S

InChI: InChI=1/C10H14O5S/c1-8-2-4-10(5-3-8)16(13,14)15-7-9(12)6-11/h2-5,9,11-12H,6-7H2,1H3/t9-/m1/s1

SMILES: Cc1ccc(cc1)S(=O)(=O)OC[C@@H](CO)O

Synonyms:

• (r)-1-Tosyloxy-2,3-propanediol
• (2R)-2,3-dihydroxypropyl 4-methylbenzenesulfonate
• (R)-Glycerol 1-(P-Toluenesulfonate)

(R)-1-Tosyloxy-2,3-propanediol

CAS: 41274-09-3

Formula: C₁₀H₁₄O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 246.2802

Ref: IN-DA003C8B

(R)-1-Tosyloxy-2,3-propanediol

Controlled Product

CAS: 41274-09-3

Applications A chiral synthon for general asymmetric synthesis. An intermediate for the synthesis of chiral aryloxypropanolamines, which make up the majority of known potent beta-adrenergic blockers.
References Fuji, M., et al.: Chem. Pharm. Bull., 40, 2353 (1992), Meerpoel, L., et al.: J. Med. Chem., 48, 2184 (2005),

Formula: C₁₀H₁₄O₅S

Color and Shape: Neat

Molecular weight: 246.28

Ref: TR-T685000

(R)-1-Tosyloxy-2,3-propanediol-d2

Controlled Product

CAS: 41274-09-3

Applications (R)-1-Tosyloxy-2,3-propanediol-d2 is an intermediate used in the synthesis of (S)-PA 824-d4 (P122502), which is a labelled novel anti-tuberculosis drug.
References Diacon, A.H. et al.: Antimicrob. Anents Chemother., 54, 3402 (2010); Dogra, M. et al.: Br. J. Pharmacol., 162, 226 (2010); Ginsberg, A.M. et al.: Antimicrob. Agents Chemother., 53, 3720 (2009);

Formula: C₁₀D₂H₁₂O₅S

Color and Shape: Neat

Molecular weight: 248.292

Ref: TR-T685502