CAS 41294-56-8

Alfacalcidol

Description:

Alfacalcidol, with the CAS number 41294-56-8, is a synthetic analog of vitamin D, specifically a form of vitamin D3 (cholecalciferol). It is primarily used in the treatment of conditions related to calcium metabolism, such as osteoporosis and renal osteodystrophy. Alfacalcidol is characterized by its ability to enhance intestinal absorption of calcium and phosphate, thereby promoting bone health. It is a fat-soluble compound, which means it is soluble in lipids and can be stored in body fat. The substance is typically administered in its active form, which allows for a more rapid effect compared to other vitamin D compounds that require conversion in the liver and kidneys. Alfacalcidol is often preferred in patients with renal impairment, as it bypasses the need for renal activation. Its pharmacological effects include the regulation of calcium homeostasis and modulation of bone metabolism, making it an important therapeutic agent in managing various metabolic bone diseases.

Formula: C₂₇H₄₄O₂

InChI: InChI=1/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23+,24-,25?,26-,27-/m1/s1

InChI key: InChIKey=OFHCOWSQAMBJIW-AVJTYSNKSA-N

SMILES: C[C@@]12[C@](\C(=C\C=C\3/C(=C)[C@@H](O)C[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]

Synonyms:

• (1Alpha,3Beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-Triene-1,3-Diol
• (1Alpha,3Beta,5Z,7E)-Secocholesta-5,7,10(19)-Triene-1,3-Diol
• (1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol
• (1R,3S,5Z,7E,14xi)-9,10-secocholesta-5,7,10-triene-1,3-diol
• (1S)-Hydroxycalciol
• (1S,3R,5E,7Z)-9,10-secocholesta-5,7,10-triene-1,3-diol
• (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3-diol
• 1(Alpha)-Hydroxyvitamin D3
• 1,2-Hydroxy Cholecalciferol
• 1,3-Cyclohexanediol, 5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3R)-
• 1-Alpha-Hydroxycholecalciferol
• 1-Alpha-Hydroxyvitamin D
• 1-Hydroxycholecalciferol
• 1-Hydroxyvitamin D3
• 1-Hydroxyvitamin D₃
• 1-Hydroxyvitamind3
• 1-Α-Hydroxycholecalciferol
• 1Alpha-Oh-D3
• 1α(OH)D3
• 1α(OH)D₃
• 1α-Hydroxycholecalciferol
• 1α-Hydroxyvitamin D3
• 1α-Hydroxyvitamin D₃
• 7,10(19)-Triene-1,3-Diol,(1-Alpha,3-Beta,5Z,7E)-10-Secocholesta-5
• 9,10-Secocholesta-5,7,10(19)-triene-1,3-diol, (1α,3β,5Z,7E)-
• Alfacaicidol
• Alfacalcidol
• Alfarol
• Alpha Calcidol
• Alpha D3
• Alpha D₃
• Alpha-Hcl
• Alpharol
• Bondiol
• EinsAlpha
• Etalpha
• Hydroxyvitamin D3
• Oxydevit
• Tevabone
• Vitamin d3, 1alpha-hydroxy-
• α-Calcidol
• ALPHACALCIDOL
• 1(ALPHA)-HYDROXYVITAMIN D3 97+% HPLC
• 1-alpha-Hydroxycholecalciferol(1alpha,3beta,5Z,7E)-Secocholesta-5,7,10(19)-trie

Alfacalcidol

CAS: 41294-56-8

Formula: C₂₇H₄₄O₂

Purity: >95.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 400.65

Ref: 3B-A3125

ALFACALCIDOL CRS

CAS: 41294-56-8

ALFACALCIDOL CRS

Ref: 41-A0325450

ALFACALCIDOL FOR SYSTEM SUITABILITY A CRS

CAS: 41294-56-8

ALFACALCIDOL FOR SYSTEM SUITABILITY A CRS

Color and Shape: Powder

Ref: 41-Y0002125

Alfacalcidol

CAS: 41294-56-8

Formula: C₂₇H₄₄O₂

Molecular weight: 400.65

Ref: 4Z-A-401001

Alfacalcidol

CAS: 41294-56-8

Formula: C₂₇H₄₄O₂

Purity: 97.0 - 102.0 %

Color and Shape: White crystalline powder

Molecular weight: 400.6

Ref: 7W-GP9489

Alfacalcidol

CAS: 41294-56-8

Alfacalcidol

Purity: ≥98%

Molecular weight: 400.64g/mol

Ref: 54-BUP02065

1a-hydroxy Vitamin D3

CAS: 41294-56-8

Formula: C27H44O2

Purity: >95%

Color and Shape: Solid

Molecular weight: 400.64

Ref: 48-60-1476

Alfacalcidol

Controlled Product

CAS: 41294-56-8

Formula: C₂₇H₄₄O₂

Color and Shape: Neat

Molecular weight: 400.64

Ref: 86-MM3002.00

Alfacalcidol

CAS: 41294-56-8

Alfacalcidol (Etalpha) (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.

Formula: C₂₇H₄₄O₂

Purity: 99.38%

Color and Shape: Solid

Molecular weight: 400.64

Ref: TM-T6374

Alfacalcidol-d7

CAS: 41294-56-8

Formula: C₂₇H₃₇D₇O₂

Molecular weight: 407.69

Ref: 4Z-A-401005

Alfacalcidol

Controlled Product

CAS: 41294-56-8

Stability Light and Temperature Sensitive
Applications A synthetic analog of Calcitiol (the hormonal form of vitamin D3), which shows identical potency with respect to stimulation of intestinal calcium absorption and bone mineral mobilization. Vitamin D source.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Formula: C₂₇H₄₄O₂

Color and Shape: Off White

Molecular weight: 400.64

Ref: TR-A524000

Alfacalcidol

CAS: 41294-56-8

Alfacalcidol is a form of vitamin D that is used to treat metabolic disorders such as hypocalcemia and hypoparathyroidism. It is a potent inducer of enzymes in the liver, which convert vitamin D into its active form. Alfacalcidol has been shown to be effective in the treatment of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. Alfacalcidol has also been shown to have calcium-regulating properties in the body. This drug may also be used for the treatment of congestive heart failure, high blood pressure, and diabetes mellitus type 2. Alfacalcidol is metabolized by hydroxylation to 25-hydroxycalcifediol and then to calcitriol, which binds with calcium ions in order to regulate serum calcium levels. This drug can be administered orally or intravenously.

Formula: C₂₇H₄₄O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 400.64 g/mol

Ref: 3D-FA17275

Alfacalcidol-d7

Controlled Product

CAS: 41294-56-8

Formula: C₂₇D₇H₃₇O₂

Color and Shape: Neat

Molecular weight: 407.68

Ref: TR-A524002

Alfacalcidol

CAS: 41294-56-8

Color and Shape: Neat

Ref: 61-FOR3002.00