CAS 41294-56-8: Alfacalcidol
Description:Alfacalcidol, with the CAS number 41294-56-8, is a synthetic analog of vitamin D, specifically a form of vitamin D3 (cholecalciferol). It is primarily used in the treatment of conditions related to calcium metabolism, such as osteoporosis and renal osteodystrophy. Alfacalcidol is characterized by its ability to enhance intestinal absorption of calcium and phosphate, thereby promoting bone health. It is a fat-soluble compound, which means it is soluble in lipids and can be stored in body fat. The substance is typically administered in its active form, which allows for a more rapid effect compared to other vitamin D compounds that require conversion in the liver and kidneys. Alfacalcidol is often preferred in patients with renal impairment, as it bypasses the need for renal activation. Its pharmacological effects include the regulation of calcium homeostasis and modulation of bone metabolism, making it an important therapeutic agent in managing various metabolic bone diseases.
Formula:C27H44O2
InChI:InChI=1S/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23-,24-,25+,26+,27-/m1/s1
InChI key:InChIKey=OFHCOWSQAMBJIW-AVJTYSNKSA-N
SMILES:OC1C(=C)C(=CC=C2CCCC3(C)C2CCC3C(C)CCCC(C)C)CC(O)C1
- Synonyms:
- (1Alpha,3Beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-Triene-1,3-Diol
- (1Alpha,3Beta,5Z,7E)-Secocholesta-5,7,10(19)-Triene-1,3-Diol
- (1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol
- (1R,3S,5Z,7E,14xi)-9,10-secocholesta-5,7,10-triene-1,3-diol
- (1S)-Hydroxycalciol
- (1S,3R,5E,7Z)-9,10-secocholesta-5,7,10-triene-1,3-diol
- (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3-diol
- 1(Alpha)-Hydroxyvitamin D3
- 1,2-Hydroxy Cholecalciferol
- 1,3-Cyclohexanediol, 5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3R)-
- See more synonyms
- 1-Alpha-Hydroxycholecalciferol
- 1-Alpha-Hydroxyvitamin D
- 1-Hydroxycholecalciferol
- 1-Hydroxyvitamin D3
- 1-Hydroxyvitamin D<sub>3</sub>
- 1-Hydroxyvitamind3
- 1-Α-Hydroxycholecalciferol
- 1Alpha-Oh-D3
- 1α(OH)D3
- 1α(OH)D<sub>3</sub>
- 1α-Hydroxycholecalciferol
- 1α-Hydroxyvitamin D3
- 1α-Hydroxyvitamin D<sub>3</sub>
- 7,10(19)-Triene-1,3-Diol,(1-Alpha,3-Beta,5Z,7E)-10-Secocholesta-5
- 9,10-Secocholesta-5,7,10(19)-triene-1,3-diol, (1α,3β,5Z,7E)-
- Alfacaicidol
- Alfacalcidol
- Alfarol
- Alpha Calcidol
- Alpha D3
- Alpha D<sub>3</sub>
- Alpha-Hcl
- Alpharol
- Bondiol
- EinsAlpha
- Etalpha
- Hydroxyvitamin D3
- Oxydevit
- Tevabone
- Vitamin d3, 1alpha-hydroxy-
- α-Calcidol
