CAS 412950-27-7

Goxalapladib

Description:

Goxalapladib, with the CAS number 412950-27-7, is a chemical compound that belongs to the class of small molecules designed as a lipoprotein-associated phospholipase A2 inhibitor. It is primarily investigated for its potential therapeutic applications in cardiovascular diseases, particularly in reducing inflammation and atherosclerosis. The compound works by inhibiting the activity of the enzyme lipoprotein-associated phospholipase A2, which is implicated in the inflammatory processes associated with cardiovascular conditions. Goxalapladib has been studied in various clinical trials to assess its efficacy and safety profile. Its chemical structure features specific functional groups that contribute to its biological activity, although detailed structural information is typically found in specialized chemical databases. As with many investigational drugs, the pharmacokinetics, metabolism, and potential side effects are critical areas of research to determine its suitability for clinical use. Overall, Goxalapladib represents a promising avenue in the development of therapies aimed at mitigating cardiovascular risk factors.

Formula: C₄₀H₃₉F₅N₄O₃

Synonyms:

• 2-[2-(2,3-Difluorophenyl)ethyl]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1,8-naphthyridine-1(4H)-acetamide

Goxalapladib

CAS: 412950-27-7

Goxalapladib

Purity: ≥98%

Molecular weight: 718.75g/mol

Ref: 54-BUP00659

Goxalapladib

CAS: 412950-27-7

Goxalapladib is a recombinant protein that stimulates homologous recombination, which is the repair of double-stranded DNA breaks. It is a particle that encompasses a recombinant adenoviral vector and a DNA sequence encoding for a gene targeted to the host cell chromosome. Goxalapladib has shown to be effective in treating heart diseases and cardiovascular diseases by reducing stenosis caused by coronary artery disease.

Formula: C₄₀H₃₉F₅N₄O₃

Purity: Min. 95%

Molecular weight: 718.75 g/mol

Ref: 3D-FG104321

Goxalapladib

CAS: 412950-27-7

Goxalapladib（GSK 677116） is a small molecule compound that can be used to treat cardiovascular risks associated with atherosclerosis.

Formula: C₄₀H₃₉F₅N₄O₃

Purity: 99.64% - 99.93%

Color and Shape: Solid

Molecular weight: 718.75

Ref: TM-T67799