CAS 41303-74-6

(4aS,6R,8aS)-3-methoxy-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-ol

Description:

The chemical substance known as (4aS,6R,8aS)-3-methoxy-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-ol, with the CAS number 41303-74-6, is a complex organic compound characterized by its unique bicyclic structure that incorporates both benzofuro and benzazepine moieties. This compound features multiple stereocenters, which contribute to its specific three-dimensional configuration, influencing its biological activity and interactions. The presence of a methoxy group enhances its solubility and may affect its pharmacological properties. Additionally, the hexahydro framework indicates that it is a saturated compound, which may impact its reactivity and stability. Such compounds are often of interest in medicinal chemistry due to their potential therapeutic applications, particularly in neuropharmacology or as modulators of neurotransmitter systems. The specific stereochemistry and functional groups present in this molecule are crucial for understanding its mechanism of action and potential uses in drug development.

Formula: C₁₆H₁₉NO₃

InChI: InChI=1/C16H19NO3/c1-19-12-3-2-10-9-17-7-6-16-5-4-11(18)8-13(16)20-15(12)14(10)16/h2-5,11,13,17-18H,6-9H2,1H3/t11-,13-,16-/m0/s1

SMILES: COc1ccc2CNCC[C@@]34C=C[C@@H](C[C@@H]3Oc1c24)O

Synonyms:

• 6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-, (4aS,6R,8aS)-

Galantamine EP Impurity E (N-Desmethyl Galanthamine)

CAS: 41303-74-6

Formula: C₁₆H₁₉NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 273.33

Ref: 4Z-G-011

N-Desmethyl Galanthamine

CAS: 41303-74-6

N-Desmethyl Galanthamine exhibits inhibitory activity against Acetylcholinesterase (AChE) and Cholinesterase (ChE), Alzheimer's disease.

Formula: C₁₆H₁₉NO₃

Purity: 98.78%

Color and Shape: Solid

Molecular weight: 273.33

Ref: TM-TN7055

(4aS,6R,8aS)-3-Methoxy-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-ol

CAS: 41303-74-6

(4aS,6R,8aS)-3-Methoxy-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-ol

Purity: 99%

Molecular weight: 273.33g/mol

Ref: 54-OR1074557

N-Desmethyl Galanthamine

CAS: 41303-74-6

Formula: C₁₆H₁₉NO₃

Molecular weight: 273.33

Ref: 7W-GY1383

N-Desmethyl Galanthamine

CAS: 41303-74-6

Formula: C₁₆H₁₉NO₃

Purity: 95%~99%

Molecular weight: 273.332

Ref: BP-BP4434

N-Desmethyl Galanthamine

Controlled Product

CAS: 41303-74-6

Impurity Galanthamine EP impurity E
Applications A metabolite of Galanthamine (G188500), a selective acetylcholinesterase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bickel, U., et al.: Clin. Pharmacol. Ther., 50, 420 (1991), Mannens, G., et al.: Drug Metab. Dispos., 30, 553 (2002), Zhao, Q., et al.: J. Clin. Pharmacol., 42, 428 (2002), Geerts, H., et al.: Brain Res., 1033, 186 (2005),

Formula: C₁₆H₁₉NO₃

Color and Shape: White To Light Yellow

Molecular weight: 273.327

Ref: TR-D292035

N-Desmethyl galanthamine

Controlled Product

CAS: 41303-74-6

N-Desmethyl galanthamine is a plant alkaloid that is found in the Huperzia serrata plant. It has been shown to have cholinergic activity and calcium binding properties. N-Desmethyl galanthamine inhibits acetylcholinesterase, an enzyme responsible for the breakdown of acetylcholine, which is a neurotransmitter. This inhibition leads to increased levels of acetylcholine, which results in increased neuron stimulation and improved memory function. N-Desmethyl galanthamine also binds to β2 nicotinic receptor sites and blocks the binding of nicotine, leading to decreased nicotine dependence.

Formula: C₁₆H₁₉NO₃

Purity: Min. 95%

Molecular weight: 273.33 g/mol

Ref: 3D-ID21271

N-Desmethyl Galanthamine

CAS: 41303-74-6

Purity: 98%

Molecular weight: 273.332

Ref: 10-F987305

Galantamine EP Impurity E

CAS: 41303-74-6

Formula: C₁₆H₁₉NO₃

Molecular weight: 273.33

Ref: ST-EA-CP-G10006