CAS 4135-11-9

(6R)-N-[(2S)-4-amino-1-{[(2S,3R)-1-{[(2S)-4-amino-1-oxo-1-{[(3S,6R,9S,12S,15S,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]amino}butan-2-y

Description:

The chemical substance with the name provided is a complex peptide derivative, characterized by its intricate structure that includes multiple amino acid residues and a cyclic framework. It features a heptaazacyclotricosane core, which is a cyclic compound containing nitrogen atoms in its ring structure, contributing to its potential biological activity. The presence of multiple amino groups suggests that it may exhibit strong interactions with biological targets, such as enzymes or receptors. Additionally, the compound's structure includes various functional groups, such as amines and carbonyls, which can influence its solubility, stability, and reactivity. The stereochemistry indicated by the (R) and (S) designations suggests that the molecule has specific spatial arrangements that are crucial for its biological function. Overall, this substance is likely to be of interest in medicinal chemistry and pharmacology due to its potential therapeutic applications, although its complexity may also pose challenges in synthesis and characterization.

Formula: C₅₆H₉₈N₁₆O₁₃

InChI: InChI=1/C56H98N16O13/c1-7-32(4)13-11-12-16-44(75)63-36(17-23-57)51(80)72-46(34(6)74)56(85)68-39(20-26-60)48(77)67-41-22-28-62-55(84)45(33(5)73)71-52(81)40(21-27-61)65-47(76)37(18-24-58)66-53(82)42(29-31(2)3)69-54(83)43(30-35-14-9-8-10-15-35)70-49(78)38(19-25-59)64-50(41)79/h8-10,14-15,31-34,36-43,45-46,73-74H,7,11-13,16-30,57-61H2,1-6H3,(H,62,84)(H,63,75)(H,64,79)(H,65,76)(H,66,82)(H,67,77)(H,68,85)(H,69,83)(H,70,78)(H,71,81)(H,72,80)/t32-,33-,34-,36+,37+,38+,39+,40-,41+,42+,43+,45+,46+/m1/s1

Polymyxin B1 Pentatrifluoroacetate

CAS: 4135-11-9

Formula: C₅₆H₉₈N₁₆O₁₃·5C₂HF₃O₂

Color and Shape: White To Off-White Solid

Molecular weight: 1203.50 5*114.02

Ref: 4Z-PP-321001

Polymyxin B1 Ditrifluoroacetate

CAS: 4135-11-9

Formula: C₅₆H₉₈N₁₆O₁₃·2C₂HF₃O₂

Molecular weight: 1203.50 2*114.02

Ref: 4Z-PP-321009

Polymyxin B1

CAS: 4135-11-9

Polymyxin B1: potent lipopeptide against multidrug-resistant Gram-negative bacteria; from Bacillus polymyxa.

Formula: C₅₆H₉₈N₁₆O₁₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 1203.48

Ref: TM-T12518

Polymyxin B1

CAS: 4135-11-9

Formula: C₅₆H₉₈N₁₆O₁₃

Molecular weight: 1203.50

Ref: ST-EA-CP-P142014

Polymyxin B1-d3

CAS: 4135-11-9

Polymyxin B1-d3 is a polymyxin antibiotic that is effective against gram-negative bacteria. It binds to the cell membrane and causes it to leak, leading to cell lysis. Polymyxin B1-d3 has been shown to be effective against antibiotic-resistant strains of bacteria, such as Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii. The phase transition temperature for this substance is about 30 degrees Celsius, so it should not be used in patients with fever or hyperthermia. Polymyxin also has a systolic pressure lowering effect, which may be due to its ability to inhibit the synthesis of cyclic peptides.

Formula: C₅₆H₉₈N₁₆O₁₃

Purity: Min. 95%

Molecular weight: 1,203.5 g/mol

Ref: 3D-EAA13511