CAS 41372-02-5

Benzylpenicilline Benzathine

Description:

Benzylpenicillin Benzathine, also known as Benzathine Penicillin G, is a long-acting form of penicillin used primarily as an antibiotic. It is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a variety of gram-positive bacteria. The compound is a combination of benzylpenicillin and benzathine, which enhances its pharmacokinetic properties, allowing for prolonged release and sustained therapeutic levels in the bloodstream. This formulation is particularly useful in treating infections such as rheumatic fever and syphilis, as well as for prophylaxis in patients with a history of rheumatic heart disease. Benzylpenicillin Benzathine is typically administered via intramuscular injection due to its poor oral bioavailability. The substance is generally well-tolerated, although allergic reactions can occur in sensitive individuals. Its stability and solubility are influenced by pH and temperature, which are important considerations in its storage and handling. Overall, Benzylpenicillin Benzathine remains a crucial agent in the treatment of bacterial infections, particularly in settings where long-term antibiotic therapy is required.

Formula: C₄₈H₆₄N₆O₁₂S₂

InChI: InChI=1/2C16H18N2O4S.C16H20N2.4H2O/c2*1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16;;;;/h2*3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);1-10,17-18H,11-14H2;4*1H2/t2*11-,12+,14-;;;;;/m11...../s1

Synonyms:

• Penicillin G Benzathine
• (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid compound with N,N'-dibenzylethylenediamine (2:1), tetrahydrate
• 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-, (2S-(2alpha,5alpha,6beta))-, compd. with N,N'-bis(phenylmethyl)-1,2-ethanediamine (2:1), tetrahydrate
• Bicillin
• Bicillin l-a
• Penicillin G benzathine tetrahydrate
• Permapen
• (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N'-dibenzylethane-1,2-diamine hydrate (2:1:4)
• Penicillin G benzathine [usan]
• N,N'-dibenzylethane-1,2-diamine,(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,tetrahydrate
• Benzylpenicilline Benzathine
• BENZATHINE PENICILLINE G TETRAHYDRATE
• BENZYLPENICILLIN BENZATHIN

Penicillin G Benzathine

CAS: 41372-02-5

Penicillin g and its salts

Formula: C₁₆H₂₀N₂·2C₁₆H₁₈N₂O₄S·4H₂O

Color and Shape: Powder

Molecular weight: 980.40236

Ref: 45-1502009

Benzathine Penicilline G Tetrahydrate

CAS: 41372-02-5

Formula: C₄₈H₆₄N₆O₁₂S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 981.1848

Ref: IN-DA00BZMN

Benzathine penicillin G tetrahydrate

CAS: 41372-02-5

Formula: C₄₈H₅₆N₆O₈S₂·4H₂O

Purity: ≥ 98.0%

Color and Shape: White to faint yellow or faint beige powder or crystals

Molecular weight: 981.18

Ref: 7W-GP9481

Penicillin G benzathine tetrahydrate

CAS: 41372-02-5

Penicillin G Benzathine Tetrahydrate (Benzathine Benzylpenicillin Tetrahydrate) serves as an antibiotic effective against numerous bacterial infections [1].

Formula: C₄₈H₆₄N₆O₁₂S₂

Color and Shape: Solid

Molecular weight: 981.18

Ref: TM-T75662

Penicillin G Benzathine Tetrahydrate

Controlled Product

CAS: 41372-02-5

Applications Penicillin G Benzathine is an antimicrobial medicament. Used in the treatment of pneumococcus and streptococcus bacterial infections.
References Tanaka, M. et al.: Antimicrob. Agents Chemother., 49, 88 (2005); Song, J. et al.: Epidemio. Infect., 140, 1267 (2012); Gamella, M. et al.: Analyst, 138, 2013 (2013);

Formula: C₁₆H₂₀N₂·2C₁₆H₁₈N₂O₄S·4H₂O

Color and Shape: Neat

Molecular weight: 981.18

Ref: TR-P223410

Penicillin G benzathine tetrahydrate

CAS: 41372-02-5

Penicillin G benzathine tetrahydrate is a form of penicillin that belongs to the group of antimicrobial agents. It is used in the treatment and prevention of streptococcal pharyngitis. This drug also has an effect on congestive heart failure, which may be due to its ability to inhibit the production of tumor necrosis factor-α (TNF-α) and serum enzymes, such as dismutase activity. Penicillin G benzathine tetrahydrate has been shown to have statistically significant effects on infectious diseases and autoimmune diseases, including syphilis, when compared with other antibiotics.

Formula: C₃₂H₃₆N₄O₈S₂·C₁₆H₂₀N₂·4H₂O

Purity: Min. 95%

Molecular weight: 981.19 g/mol

Ref: 3D-FP33369

Benzylpenicillin (benzathine) tetrahydrate

CAS: 41372-02-5

Formula: C₁₆H₂₀N₂(C₁₆H₁₈N₂O₄S)H₂O

Molecular weight: 240.4 : 2(334.4) : 4(18.0)

Ref: ST-EA-CP-B213018

Benzylpenicillin (benzathine) tetrahydrate

CAS: 41372-02-5

Formula: C₁₆H₂₀N₂(C₁₆H₁₈N₂O₄S)H₂O

Molecular weight: 240.4 : 2(334.4) : 4(18.0)

Ref: ST-EA-CP-P39017