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CAS 41372-02-5

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Benzylpenicilline Benzathine

Description:
Benzylpenicillin Benzathine, also known as Benzathine Penicillin G, is a long-acting form of penicillin used primarily as an antibiotic. It is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a variety of gram-positive bacteria. The compound is a combination of benzylpenicillin and benzathine, which enhances its pharmacokinetic properties, allowing for prolonged release and sustained therapeutic levels in the bloodstream. This formulation is particularly useful in treating infections such as rheumatic fever and syphilis, as well as for prophylaxis in patients with a history of rheumatic heart disease. Benzylpenicillin Benzathine is typically administered via intramuscular injection due to its poor oral bioavailability. The substance is generally well-tolerated, although allergic reactions can occur in sensitive individuals. Its stability and solubility are influenced by pH and temperature, which are important considerations in its storage and handling. Overall, Benzylpenicillin Benzathine remains a crucial agent in the treatment of bacterial infections, particularly in settings where long-term antibiotic therapy is required.
Formula:C48H64N6O12S2
InChI:InChI=1/2C16H18N2O4S.C16H20N2.4H2O/c2*1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16;;;;/h2*3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);1-10,17-18H,11-14H2;4*1H2/t2*11-,12+,14-;;;;;/m11...../s1
Synonyms:
  • Penicillin G Benzathine
  • (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid compound with N,N'-dibenzylethylenediamine (2:1), tetrahydrate
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-, (2S-(2alpha,5alpha,6beta))-, compd. with N,N'-bis(phenylmethyl)-1,2-ethanediamine (2:1), tetrahydrate
  • Bicillin
  • Bicillin l-a
  • Penicillin G benzathine tetrahydrate
  • Permapen
  • (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N'-dibenzylethane-1,2-diamine hydrate (2:1:4)
  • Penicillin G benzathine [usan]
  • N,N'-dibenzylethane-1,2-diamine,(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,tetrahydrate
  • See more synonyms
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