CAS 41432-67-1

8,5''-(S)-Cycloadenosine

CAS: 41432-67-1

Ref: 7W-GN2908

8,5'-(S)-Cycloadenosine

CAS: 41432-67-1

8,5'-(S)-Cycloadenosine is a radiosensitizer that is used in the treatment of cancer. It is an adenosine derivative that has been shown to increase the sensitivity of cells to radiation. 8,5'-(S)-Cycloadenosine has been used in clinical trials as a radiosensitizer for the treatment of non-small cell lung cancer and myeloma. It can be used with other chemotherapeutic agents or irradiation to reduce tumor size and improve survival rates. The compound binds to DNA and increases the formation of hydrogen peroxide by inhibiting DNA repair enzymes such as topoisomerase II, which are responsible for breaking down hydrogen peroxide. 8,5'-(S)-Cycloadenosine also prevents the production of reactive oxygen species (ROS) from azobisisobutyronitrile (AIBN), which is often used as a radical initiator during polymerization reactions.

Formula: C₁₀H₁₁N₅O₄

Purity: Min. 95%

Color and Shape: White to off-white solid.

Molecular weight: 265.23 g/mol

Ref: 3D-NC01366

8,5’(R)-Cycloadenosine

CAS: 41432-67-1

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Formula: C₁₀H₁₁N₅O₄

Purity: Min. 95%

Molecular weight: 265.23 g/mol

Ref: 3D-NC06309