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CAS 41451-91-6

:

Erythromycin E

Description:
Erythromycin E, identified by its CAS number 41451-91-6, is a macrolide antibiotic derived from the bacterium Saccharopolyspora erythraea. It exhibits a broad spectrum of antibacterial activity, particularly against Gram-positive bacteria and some Gram-negative organisms. The structure of Erythromycin E features a large lactone ring, which is characteristic of macrolides, and it contains multiple hydroxyl and ketone functional groups that contribute to its biological activity. This compound works by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit, effectively blocking the translocation step of translation. Erythromycin E is often used in clinical settings to treat various infections, including respiratory tract infections, skin infections, and certain sexually transmitted diseases. Its pharmacokinetics include oral absorption, with metabolism primarily occurring in the liver. While generally well-tolerated, it can cause gastrointestinal side effects and may interact with other medications due to its effects on liver enzymes. Overall, Erythromycin E remains an important antibiotic in the treatment of bacterial infections.
Formula:C37H65NO14
InChI:InChI=1S/C37H65NO14/c1-13-25-36(9,45)29(41)20(4)26(39)18(2)15-34(7,44)31(50-33-27(40)24(38(10)11)14-19(3)48-33)21(5)28-23(32(43)49-25)16-47-37(52-28)17-35(8,46-12)30(42)22(6)51-37/h18-25,27-31,33,40-42,44-45H,13-17H2,1-12H3/t18-,19-,20+,21+,22+,23-,24+,25-,27-,28+,29-,30+,31-,33+,34-,35-,36-,37-/m1/s1
InChI key:InChIKey=PRUSTPADOGZAML-LMXGZOGMSA-N
SMILES:O(C)[C@]1(C)C[C@]2(O[C@@]3([C@@](CO2)(C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]4[C@H](O)[C@@H](N(C)C)C[C@@H](C)O4)[C@H]3C)[H])[H])O[C@@H](C)[C@@H]1O
Synonyms:
  • Erythromycin E
  • Spiro[5H,11H-1,3-dioxino[5,4-c]oxacyclotetradecin-2,2′-[2H]pyran], erythromycin deriv.
  • Erythromycin, 1′′,16-epoxy-
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Found 3 products.
  • Erythromycin EP Impurity C (Erythromycin E)
    TLC
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    Erythromycin EP Impurity C (Erythromycin E)

    CAS:
    Formula:C37H65NO14
    Color and Shape:Off-White Solid
    Molecular weight:747.92

    Ref: 4Z-E-2016

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  • Erythromycin EP Impurity C
    Standalix
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    Erythromycin EP Impurity C

    CAS:
    Formula:C37H65NO14
    Molecular weight:747.92

    Ref: ST-EA-CP-E18003

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  • Erythromycin E
    Biosynth
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    Erythromycin E

    CAS:
    <p>Erythromycin E is a diluent that is used to make erythromycin solutions. It has been shown to have bioactive molecules by incubating it with chromatographic methods. These bioactive molecules are conjugates of erythromycin and methyl ethyl groups. Erythromycin E has also been shown to have genetic mechanisms, which may relate to its ability to inhibit the synthesis of inflammatory cytokines such as IL-1β and IL-8 in the airways. The acetate extraction method is used for the production of erythromycin E. This process involves extracting erythromycin from Streptomyces bacteria grown in an acetate buffer solution.</p>
    Formula:C37H65NO14
    Purity:Min. 95%
    Color and Shape:Off-White Solid
    Molecular weight:747.91 g/mol

    Ref: 3D-IE146282

    25mg
    4,224.00€