CAS: 414910-30-8 - 4(S)-(4-Acetylpiperazin-1-yl)-N-[1(R)-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2(R)-(4-fluoro-2-methylphenyl)-N-methylpiperidine- 1-carboxamide methanesulfonate

Formula: C₃₁H₃₉F₇N₄O₅S

InChI: InChI=1S/C30H35F7N4O2.CH4O3S/c1-18-13-24(31)5-6-26(18)27-17-25(40-11-9-39(10-12-40)20(3)42)7-8-41(27)28(43)38(4)19(2)21-14-22(29(32,33)34)16-23(15-21)30(35,36)37;1-5(2,3)4/h5-6,13-16,19,25,27H,7-12,17H2,1-4H3;1H3,(H,2,3,4)/t19-,25+,27-;/m1./s1

InChI key: InChIKey=YRFKYVWDPCOSTE-REWBLLDVSA-N

SMILES: O=C(N(C)C(C=1C=C(C=C(C1)C(F)(F)F)C(F)(F)F)C)N2CCC(N3CCN(C(=O)C)CC3)CC2C4=CC=C(F)C=C4C.O=S(=O)(O)C

Synonyms:

• (2R,4S)-4-(4-acetylpiperazin-1-yl)-N-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide methanesulfonate (1:1)
• 1-Piperidinecarboxamide, 4-(4-acetyl-1-piperazinyl)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methyl-, (2R,4S)-, methanesulfonate (1:1)
• 1-Piperidinecarboxamide, 4-(4-acetyl-1-piperazinyl)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methyl-, (2R,4S)-, monomethanesulfonate
• 4-(S)-(4-Acetylpiperazin-1-yl)-2-(R)-(4-fluoro-2-methylphenyl)piperidine-1-carboxylic acid N-[1-(R)-(3,5-bis-trifluoromethylphenyl)ethyl]-N-methylamide methanesulfonate
• Casopitant Mesilate
• Casopitant mesylate
• Gw 679769B
• Gw-579769
• Rezonic
• Zunrisa

Casopitant Mesylate

CAS: 414910-30-8

• Formula: C₃₀H₃₅F₇N₄O₂·CH₄O₃S
• Color and Shape: Neat
• Molecular weight: 712.719

Casopitant mesylate

CAS: 414910-30-8

Neurokinin 1 receptor (NK1R) antagonist

• Formula: C₃₁H₃₉F₇N₄O₅S
• Purity: Min. 95%
• Molecular weight: 712.72 g/mol

Casopitant mesylate

CAS: 414910-30-8

Casopitant mesylate (GW679769B) is a selective, brain permeable, and orally active antagonist of neurokinin 1 …

• Formula: C₃₁H₃₉F₇N₄O₅S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 712.72