CAS 41513-04-6

1-Bromo-4-chloro-2-nitrobenzene

Description:

1-Bromo-4-chloro-2-nitrobenzene is an aromatic compound characterized by the presence of a bromine atom, a chlorine atom, and a nitro group attached to a benzene ring. Its molecular formula is C6H3BrClN2O2, indicating that it contains six carbon atoms, three hydrogen atoms, one bromine atom, one chlorine atom, two nitrogen atoms, and two oxygen atoms. This compound typically appears as a yellow to brown solid and is known for its moderate solubility in organic solvents. It exhibits properties typical of halogenated nitrobenzenes, including potential applications in organic synthesis and as an intermediate in the production of dyes, pharmaceuticals, and agrochemicals. The presence of both halogen and nitro functional groups contributes to its reactivity, making it a useful building block in various chemical reactions. However, it is important to handle this compound with care due to its potential toxicity and environmental impact, as well as to follow appropriate safety protocols when working with it in a laboratory setting.

Formula: C₆H₃BrClNO₂

InChI: InChI=1/C6H3BrClNO2/c7-5-2-1-4(8)3-6(5)9(10)11/h1-3H

InChI key: InChIKey=UKTIMFAJRPSNGR-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C(Br)C=CC(Cl)=C1

Synonyms:

• 1-Bromo-2-nitro-4-chlorobenzene
• 2-Bromo-5-chloronitrobenzene
• 4-Bromo-3-nitrochlorobenzene
• 4-Chloro-2-bromonitrobenzene
• Benzene, 1-bromo-4-chloro-2-nitro-
• 1-Bromo-4-chloro-2-nitrobenzene
• 2-Nitro-4-chlorophenyl bromide
• 3-Nitro-4-bromophenyl chloride

1-Bromo-4-chloro-2-nitrobenzene, 98%

CAS: 41513-04-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₃BrClNO₂

Purity: 98%

Color and Shape: Pale cream to cream to yellow to brown, Crystals or powder or crystalline powder

Molecular weight: 236.45

Ref: 02-A12635

1-Bromo-4-chloro-2-nitrobenzene

CAS: 41513-04-6

Formula: C₆H₃BrClNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 236.4505

Ref: IN-DA003GPG

2-Bromo-5-chloronitrobenzene

CAS: 41513-04-6

2-Bromo-5-chloronitrobenzene

Formula: C₆H₃BrClNO₂

Purity: ≥95%

Color and Shape: greenish tan crystals

Molecular weight: 236.45g/mol

Ref: 54-OR27686

1-Bromo-4-chloro-2-nitrobenzene

CAS: 41513-04-6

Formula: C₆H₃BrClNO₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 236.45

Ref: 3B-B5696

2-Bromo-5-chloronitrobenzene

CAS: 41513-04-6

2-Bromo-5-chloronitrobenzene is a synthetic drug that has been shown to inhibit the growth of cancer cells. It is a potent antagonist at the tyrosine kinase receptor, which may be involved in the development of some cancers. The drug was first synthesized in 1887 by German chemists for use as an antipsychotic drug, but it was not until 1962 that researchers discovered its therapeutic value in treating schizophrenia. Clozapine also blocks the activity of other receptors including factor receptors and growth factors, which may account for its antitumor effects. Clozapine has also been used to treat resistant breast cancer cases with imatinib therapy.

Formula: C₆H₃BrClNO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 236.45 g/mol

Ref: 3D-FB64603

2-Bromo-5-chloronitrobenzene

CAS: 41513-04-6

Formula: C₆H₃BrClNO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 236.45

Ref: 10-F219364

1-Bromo-4-chloro-2-nitrobenzene

Controlled Product

CAS: 41513-04-6

Applications 1-Bromo-4-chloro-2-nitrobenzene is used in the synthesis of diindolocarbazoles used in the synthesis of ladder oligo(p-aniline)s useful in organic electronics. Also used in the synthesis of novel benzenesulfonamides for the discovery of potent cell cycle inhibitors.
References Wakim, S. et al.: Org. Lett., 6, 3413 (2004); Owa, T. et al.: Bioorg. Med. Chem. Lett., 10, 1223 (2000);

Formula: C₆H₃BrClNO₂

Color and Shape: Neat

Molecular weight: 236.45

Ref: TR-B682460