CAS 41515-13-3

N-Desmethyl Bendamustine

CAS: 41515-13-3

N-DesmethylBendamustine is a metabolite of Bendamustine. It exerts cytotoxic effects on various lymphoma cell lines and peripheral blood lymphocytes.

Formula: C₁₅H₁₉Cl₂N₃O₂

Color and Shape: Solid

Molecular weight: 344.24

Ref: TM-T203117

Bendamustine Impurity 5 (Bendamustine Desmethyl Impurity)

CAS: 41515-13-3

Formula: C₁₅H₁₉Cl₂N₃O₂

Color and Shape: White To Off-White Solid

Molecular weight: 344.24

Ref: 4Z-B-4310

Bendamustine Impurity 5-d4 (Desmethyl Impurity)

CAS: 41515-13-3

Formula: C₁₅H₁₅D₄Cl₂N₃O₂

Molecular weight: 348.26

Ref: 4Z-B-4351

N-Desmethylbendamustine

CAS: 41515-13-3

N-Desmethylbendamustine is a drug that is used to treat chronic lymphocytic leukemia. It inhibits tumor growth by binding to DNA, inhibiting transcription and replication of cancer cells. N-Desmethylbendamustine has been shown to be effective against pediatric patients with chronic lymphocytic leukemia, but its efficacy in adults is not well-established. The elimination half-life of the drug is 3 hours and it is eliminated via hepatic metabolism. The drug also has a low risk for cross-resistance with other chemotherapeutic drugs.

Formula: C₁₅H₁₉Cl₂N₃O₂

Purity: Min. 95%

Molecular weight: 344.2 g/mol

Ref: 3D-RBA51513