CAS 41598-07-6

PGD2

Description:

Prostaglandin D2 (PGD2) is a naturally occurring prostaglandin that plays a significant role in various physiological processes, including inflammation and sleep regulation. It is synthesized from arachidonic acid through the action of cyclooxygenase enzymes. PGD2 is characterized by its ability to act as a signaling molecule, binding to specific receptors such as DP1 and DP2, which are involved in mediating its effects on smooth muscle relaxation, inhibition of platelet aggregation, and modulation of immune responses. This compound is also implicated in allergic reactions and has been studied for its role in conditions like asthma and sleep disorders. In terms of its chemical structure, PGD2 features a cyclopentane ring and multiple functional groups, contributing to its biological activity. As a lipid mediator, PGD2 is typically present in low concentrations in tissues and is rapidly metabolized, which underscores its transient nature in biological systems. Its CAS number, 41598-07-6, is a unique identifier used for regulatory and research purposes.

Formula: C₂₀H₃₂O₅

InChI: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1

InChI key: InChIKey=BHMBVRSPMRCCGG-OUTUXVNYSA-N

SMILES: C(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)C(=O)C[C@@H]1O

Synonyms:

• (5Z,9alpha,13E,15S)-9,15-dihydroxy-11-oxoprosta-5,13-dien-1-oic acid
• (5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic acid
• 11-Dehydroprostaglandin F_2α
• PGD₂
• Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9α,13E,15S)-
• Prostaglandin D2
• Prostaglandin D₂
• prostaglandin D2 cell culture tested
• 11-Dehydroprostaglandin F2α
• PGD2

Prostaglandin D2 MaxSpec® Standard

CAS: 41598-07-6

Formula: C₂₀H₃₂O₅

Purity: 99%

Color and Shape: Solid

Molecular weight: 352.4651

Ref: IN-DA00C0CL

Prostaglandin D2

CAS: 41598-07-6

Formula: C₂₀H₃₂O₅

Molecular weight: 352.47

Ref: 7W-GL9125

Prostaglandin D2

CAS: 41598-07-6

Formula: C₂₀H₃₂O₅

Molecular weight: 352.47

Ref: 4Z-P-144033

Prostaglandin D2

Controlled Product

CAS: 41598-07-6

Stability Light Sensitive
Applications Prostaglandin D2 is a fatty acid compound present in the human body. Elevated levels of localized Prostaglandin D2 has been linked to hair loss and growth inhibition. It has also been seen to contribute to the activity of allergic asthma.
References Matsuoka, T. et al.: Science., 287, 2013 (2000); Luis, G. et al.: Sci. Transl., 4, 126 (2012);

Formula: C₂₀H₃₂O₅

Color and Shape: Neat

Molecular weight: 352.47

Ref: TR-P838575

Prostaglandin D2

CAS: 41598-07-6

Prostaglandin D2 is a lipid mediator and a member of the prostaglandin family. It is produced in many tissues, including the brain, lungs, heart, kidneys, and intestines. Prostaglandin D2 has been shown to be an intracellular target for nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen. NSAIDs inhibit cyclooxygenase 1 and 2 (COX-1 and COX-2) enzymes that produce prostaglandins from arachidonic acid. This inhibition leads to decreased production of prostaglandin D2 in the brain and other organs. Prostaglandin D2 has been shown to have cardiac effects by acting on receptors present in the heart cells. The response element for prostaglandin D2 is found upstream of several genes that control bowel function, including cytosolic Ca2+, polymorphonuclear leucocytes, and tight junction proteins.

Formula: C₂₀H₃₂O₅

Purity: Area-% Min. 95 Area-%

Molecular weight: 352.47 g/mol

Ref: 3D-FP176166

Prostaglandin D2

CAS: 41598-07-6

Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals,and is a potent endogenous sleep promoting substances.

Formula: C₂₀H₃₂O₅

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 352.47

Ref: TM-T13831