CAS 41621-49-2: Ciclopirox olamine
Description:Ciclopirox olamine is an antifungal agent commonly used in dermatological formulations to treat various fungal infections, including athlete's foot, ringworm, and seborrheic dermatitis. It is characterized by its broad-spectrum antifungal activity, which is attributed to its ability to inhibit the growth of fungi by interfering with their cell membrane integrity and function. Ciclopirox olamine is a white to off-white crystalline powder that is soluble in water and has a pH range that is typically neutral to slightly acidic. Its mechanism of action involves chelation of metal ions, which disrupts essential enzymatic processes in fungal cells. Additionally, ciclopirox olamine exhibits anti-inflammatory properties, making it beneficial for treating conditions that involve both fungal infection and inflammation. It is often formulated in creams, lotions, and shampoos for topical application. Safety profiles indicate that it is generally well-tolerated, with minimal systemic absorption when used as directed. However, like all medications, it may cause localized irritation or allergic reactions in some individuals.
Formula:C12H17NO2·C2H7NO
InChI:InChI=1S/C12H17NO2.C2H7NO/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10;3-1-2-4/h7-8,10,15H,2-6H2,1H3;4H,1-3H2
InChI key:InChIKey=MBRHNTMUYWQHMR-UHFFFAOYSA-N
SMILES:O=C1C=C(C=C(N1O)C2CCCCC2)C.OCCN
- Synonyms:
- 1-Hydroxy-4-methyl-6-cyclohexyl-2-pyridinone ethanolamine salt
- 2(1H)-Pyridinone, 6-cyclohexyl-1-hydroxy-4-methyl-, compd. with 2-aminoethanol (1:1)
- 6-Cyclohexyl-1-Hydroxy-4-Methyl-1H-Pyridin-2-One, 2-Amino-Ethanol
- 6-Cyclohexyl-1-Hydroxy-4-Methyl-2(1H)-Pyridone Ethanolammonium Salt
- 6-Cyclohexyl-1-Hydroxy-4-Methyl-2[1H]-Pyridone Ethanolamine Salt
- 6-Cyclohexyl-1-Hydroxy-4-Methylpyridin-2(1H)-One 2-Aminoethanol (1:1)
- Batrafen
- Brumixol
- Ciclochem
- Ciclopirox Ethanolamine
- See more synonyms
- Ciclopirox ethanolamine (1:1)
- Ethanol, 2-amino-, compd. with 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone (1:1)
- Fungowas
- Hoe 296
- Loprox
- Micoxolamina
- Mycoster
- NSC 336278
- Sebiprox
- Selergo
- Terit
- Ciclopirox olamine
