CAS 41667-95-2

5,6-Dichloronicotinic acid

Description:

5,6-Dichloronicotinic acid is a heterocyclic aromatic compound that belongs to the class of chlorinated derivatives of nicotinic acid. It features a pyridine ring with two chlorine substituents at the 5 and 6 positions, along with a carboxylic acid functional group at the 3-position. This compound is typically a white to off-white crystalline solid, exhibiting moderate solubility in polar solvents such as water and ethanol. Its molecular structure contributes to its potential applications in pharmaceuticals, agrochemicals, and as a building block in organic synthesis. The presence of chlorine atoms enhances its reactivity and can influence its biological activity, making it of interest in medicinal chemistry. Additionally, 5,6-Dichloronicotinic acid may exhibit specific properties such as acidity, which can be characterized by its pKa values, and it may participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. Safety data should be consulted for handling and storage, as with any chemical substance.

Formula: C₆H₃Cl₂NO₂

InChI: InChI=1S/C6H3Cl2NO2/c7-4-1-3(6(10)11)2-9-5(4)8/h1-2H,(H,10,11)

InChI key: InChIKey=RNRLTTNKVLFZJS-UHFFFAOYSA-N

SMILES: C(O)(=O)C=1C=C(Cl)C(Cl)=NC1

Synonyms:

• 2,3-Dichloropyridine-5-carboxylic acid
• 3-Pyridinecarboxylic acid, 5,6-dichloro-
• 5,6-Dichloro Nicotinic Acid
• 5,6-Dichloro-3-pyridinecarboxylic acid
• 5,6-Dichloropyridine-3-carboxylic acid
• NSC 63885
• Nicotinic acid, 5,6-dichloro-
• 5,6-Dichloronicotinic acid

5,6-Dichloronicotinic acid

CAS: 41667-95-2

Formula: C₆H₃Cl₂NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 191.9995

Ref: IN-DA003466

5,6-Dichloronicotinic acid

CAS: 41667-95-2

Formula: C₆H₃Cl₂NO₂

Molecular weight: 192.00

Ref: 7W-GK8648

5,6-Dichloronicotinic acid

CAS: 41667-95-2

5,6-Dichloronicotinic acid

Formula: C₆H₃Cl₂NO₂

Purity: 97%

Color and Shape: solid

Molecular weight: 192.00g/mol

Ref: 54-OR1909

5,6-Dichloronicotinic Acid

CAS: 41667-95-2

Formula: C₆H₃Cl₂NO₂

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 192.00

Ref: 3B-D2401

5,6-Dichloronicotinic acid

CAS: 41667-95-2

Formula: C₆H₃Cl₂NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 192

Ref: 10-F010699

5,6-Dichloronicotinic acid

Controlled Product

CAS: 41667-95-2

Applications 5,6-Dichloronicotinic Acid functions as a multifunctional agent for Alzheimer treatment.
References Czarnecka, K., et al.: J. Enzyme Inhib. Med. Chem., 33, 158 (2018)

Formula: C₆H₃Cl₂NO₂

Color and Shape: Neat

Molecular weight: 192.0

Ref: TR-D435653

5,6-Dichloronicotinic Acid

CAS: 41667-95-2

Formula: C₆H₃Cl₂NO₂

Molecular weight: 192

Ref: ST-EA-CP-N50007

5,6-Dichloronicotinic acid

CAS: 41667-95-2

5,6-Dichloronicotinic acid is a compound that can be synthesized by reacting methyl ketones with chloroacetic acid. It is used in the synthesis of maleic anhydride and has been shown to inhibit the catalysis of acetylcholine chloride. 5,6-Dichloronicotinic acid has also been shown to have an inhibitory effect on Alzheimer's disease. The kinetic mechanism for this inhibition occurs through the hydrolysis step of 5,6-Dichloronicotinic acid by magnesium chloride in hexane solution. The reactive acylation reaction proceeds when 5,6-Dichloronicotinic acid reacts with acetic anhydride in the presence of pyridine.

Formula: C₆H₃Cl₂NO₂

Color and Shape: Powder

Molecular weight: 192 g/mol

Ref: 3D-FD57268

5,6-Dichloronicotinic acid

CAS: 41667-95-2

5,6-Dichloronicotinic acid (catalog number: T67674, CAS number: 41667-95-2) is a valuable organic compound for life sciences research.

Formula: C₆H₃Cl₂NO₂

Color and Shape: Solid

Molecular weight: 192

Ref: TM-T67674