CAS 41733-55-5

Furosemide sodium

Description:

Furosemide sodium, with the CAS number 41733-55-5, is a potent loop diuretic commonly used in the treatment of conditions such as edema associated with heart failure, liver cirrhosis, and renal disease, as well as hypertension. It functions by inhibiting the sodium-potassium-chloride co-transporter in the thick ascending limb of the loop of Henle in the nephron, leading to increased excretion of sodium, chloride, and water. This results in diuresis, which helps reduce fluid overload. Furosemide sodium is typically administered orally or intravenously and is known for its rapid onset of action. The compound is characterized by its solubility in water, which facilitates its use in clinical settings. Side effects may include electrolyte imbalances, dehydration, and potential ototoxicity, particularly with rapid intravenous administration. As a sulfonamide derivative, it shares structural similarities with other diuretics but is distinguished by its specific mechanism of action and therapeutic applications. Overall, furosemide sodium is a critical medication in managing fluid balance and blood pressure in various medical conditions.

Formula: C₁₂H₁₁ClN₂O₅S·Na

InChI: InChI=1S/C12H11ClN2O5S.Na/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19;/h1-5,15H,6H2,(H,16,17)(H2,14,18,19);

InChI key: InChIKey=RSDYORUXBHNXHC-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(NCC2=CC=CO2)C=C(Cl)C(S(N)(=O)=O)=C1.[Na]

Synonyms:

• Sodium furosemide
• Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]-, monosodium salt
• Furosemide sodium
• Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]-, sodium salt (1:1)

Furosemide (sodium)

CAS: 41733-55-5

Formula: C₁₂H₁₀ClN₂NaO₅S

Purity: 98%

Molecular weight: 352.7260

Ref: IN-DA0075I7

Furosemide sodium

CAS: 41733-55-5

Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.

Formula: C₁₂H₁₀ClN₂NaO₅S

Purity: 99.52% - >99.99%

Color and Shape: Solid

Molecular weight: 352.73

Ref: TM-T35336

Furosemide sodium

Controlled Product

CAS: 41733-55-5

Furosemide is an organic solvent that is used as a salt of furosemide sodium. It has been shown to have strong absorption in the UV range, which can be used for cellular and environmental pollution. Furosemide is also a natriuretic drug that is used to decrease blood pressure and to prevent and treat heart failure. Furosemide may be given orally or intravenously, which will lead to an increase in plasma albumin levels. This drug also binds to surfactant proteins, which are necessary for maintaining the stability of lung surfactant and preventing it from collapsing on itself. Furosemide inhibits the formation of calcium carbonate precipitates by chelating magnesium ions from solution. The drug also has a hydrodynamic effect on electrolytes such as sodium, potassium, and chloride ions. This leads to increased urinary excretion of these ions and a reduction in their concentrations in the blood plasma.
Furosemide is often formulated with other

Formula: C₁₂H₁₀ClN₂NaO₅S

Purity: Min. 95%

Molecular weight: 352.73 g/mol

Ref: 3D-RBA73355