CAS 41733-55-5: Furosemide sodium

Description: Furosemide sodium, with the CAS number 41733-55-5, is a potent loop diuretic commonly used in the treatment of conditions such as edema associated with heart failure, liver cirrhosis, and renal disease, as well as hypertension. It functions by inhibiting the sodium-potassium-chloride co-transporter in the thick ascending limb of the loop of Henle in the nephron, leading to increased excretion of sodium, chloride, and water. This results in diuresis, which helps reduce fluid overload. Furosemide sodium is typically administered orally or intravenously and is known for its rapid onset of action. The compound is characterized by its solubility in water, which facilitates its use in clinical settings. Side effects may include electrolyte imbalances, dehydration, and potential ototoxicity, particularly with rapid intravenous administration. As a sulfonamide derivative, it shares structural similarities with other diuretics but is distinguished by its specific mechanism of action and therapeutic applications. Overall, furosemide sodium is a critical medication in managing fluid balance and blood pressure in various medical conditions.

Formula: C₁₂H₁₁ClN₂O₅S·Na

InChI: InChI=1S/C12H11ClN2O5S.Na/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19;/h1-5,15H,6H2,(H,16,17)(H2,14,18,19);

InChI key: InChIKey=RSDYORUXBHNXHC-UHFFFAOYSA-N

SMILES: [Na].O=C(O)C1=CC(=C(Cl)C=C1NCC=2OC=CC2)S(=O)(=O)N

Synonyms:

• Sodium furosemide
• Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]-, monosodium salt
• Furosemide sodium
• Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]-, sodium salt (1:1)

Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]-,monosodium salt

CAS: 41733-55-5

• Formula: C₁₂H₁₀ClN₂NaO₅S
• Purity: 98%
• Molecular weight: 352.726

Furosemide sodium

CAS: 41733-55-5

Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.

• Formula: C₁₂H₁₀ClN₂NaO₅S
• Purity: 100%
• Color and Shape: Liquid
• Molecular weight: 352.73

Furosemide sodium

CAS: 41733-55-5

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• Formula: C₁₂H₁₀ClN₂NaO₅S
• Purity: Min. 95%
• Molecular weight: 352.73 g/mol