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CAS 41744-40-5

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Sulbenicillin

Description:
Sulbenicillin is a semi-synthetic antibiotic belonging to the penicillin class, primarily used for its antibacterial properties. It is characterized by its beta-lactam structure, which is essential for its mechanism of action, inhibiting bacterial cell wall synthesis. Sulbenicillin is effective against a range of gram-positive and some gram-negative bacteria, making it useful in treating various infections. The compound is typically administered in its sodium salt form to enhance solubility and bioavailability. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion, with renal clearance being a significant route of elimination. Sulbenicillin may exhibit resistance in certain bacterial strains due to the production of beta-lactamases, enzymes that can hydrolyze the beta-lactam ring. As with other antibiotics, it is crucial to use sulbenicillin judiciously to minimize the development of resistance and ensure its efficacy in clinical settings. Potential side effects may include allergic reactions, gastrointestinal disturbances, and alterations in normal flora. Overall, sulbenicillin remains a valuable tool in the antibiotic arsenal, particularly for specific infections.
Formula:C16H18N2O7S2
InChI:InChI=1S/C16H18N2O7S2/c1-16(2)11(15(21)22)18-13(20)9(14(18)26-16)17-12(19)10(27(23,24)25)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,17,19)(H,21,22)(H,23,24,25)/t9-,10-,11+,14-/m1/s1
InChI key:InChIKey=JETQIUPBHQNHNZ-NJBDSQKTSA-N
SMILES:C(O)(=O)[C@@H]1N2[C@@]([C@H](NC([C@H](S(=O)(=O)O)C3=CC=CC=C3)=O)C2=O)(SC1(C)C)[H]
Synonyms:
  • (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[[(2R)-2-phenyl-2-sulfoacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • (2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[phenyl(sulfo)acetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylsulfoacetyl)amino]-, [2S-[2α,5α,6β(S*)]]-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-2-phenyl-2-sulfoacetyl]amino]-, (2S,5R,6R)-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-phenylsulfoacetyl]amino]-, (2S,5R,6R)-
  • <span class="text-smallcaps">D</span>-(-)-Sulbenicillin
  • Arsonate
  • Sulbenicillin, <span class="text-smallcaps">D</span>-(-)-
  • α-Sulfobenzylpenicillin
  • D-(-)-Sulbenicillin
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Found 4 products.
  • Sulbenicillin
    Glentham
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    Sulbenicillin

    CAS:
    Formula:C16H18N2O7S2
    Molecular weight:414.45

    Ref: 7W-GP9656

    ne
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  • Sulbenicillin
    Targetmol
    + Info

    Sulbenicillin

    CAS:
    <p>Sulbenicillin is an alpha-sulfobenzylpenicillin. It has been used in combination with dibekacin.</p>
    Formula:C16H18N2O7S2
    Purity:98%
    Color and Shape:White Crystalline Powder
    Molecular weight:414.45

    Ref: TM-T20254

  • Sulbenicillin
    TLC
    + Info

    Sulbenicillin

    CAS:
    Formula:C16H18N2O7S2
    Molecular weight:414.45

    Ref: 4Z-S-133001

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    10mg
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    25mg
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    50mg
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    100mg
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  • Sulbenicillin
    Biosynth
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    Sulbenicillin

    CAS:
    <p>Sulbenicillin is a semi-synthetic penicillin antibiotic, which is derived from 6-aminopenicillanic acid, a natural precursor in the biosynthesis of penicillins. With its beta-lactam structure, Sulbenicillin disrupts bacterial cell wall synthesis by inhibiting penicillin-binding proteins, which are essential enzymes in the cross-linking of peptidoglycan layers. This disruption compromises the structural integrity of the bacterial cell wall, resulting in cell lysis and death, particularly in Gram-negative bacteria.</p>
    Formula:C16H18N2O7S2
    Purity:Min. 95%
    Molecular weight:414.46 g/mol

    Ref: 3D-FS173085

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