CAS 4176-97-0
:Deoxyandrographolide
Description:
Deoxyandrographolide is a natural compound derived from the plant Andrographis paniculata, commonly known for its medicinal properties. It belongs to the class of compounds known as diterpenoids and is characterized by its complex bicyclic structure. This compound exhibits a range of biological activities, including anti-inflammatory, antimicrobial, and anticancer properties, making it of interest in pharmacological research. Deoxyandrographolide is typically found in the form of a white to off-white crystalline powder and is soluble in organic solvents but has limited solubility in water. Its mechanism of action often involves modulation of various signaling pathways, contributing to its therapeutic effects. The compound's safety profile and potential side effects are still under investigation, highlighting the need for further studies to fully understand its pharmacokinetics and pharmacodynamics. Overall, deoxyandrographolide represents a promising candidate for drug development, particularly in the context of traditional medicine and modern therapeutic applications.
Formula:C20H30O4
InChI:InChI=1S/C20H30O4/c1-13-4-7-16-19(2,10-8-17(22)20(16,3)12-21)15(13)6-5-14-9-11-24-18(14)23/h9,15-17,21-22H,1,4-8,10-12H2,2-3H3/t15-,16+,17-,19+,20+/m1/s1
InChI key:InChIKey=GVRNTWSGBWPJGS-YSDSKTICSA-N
SMILES:C[C@]12[C@@]([C@@](CO)(C)[C@H](O)CC1)(CCC(=C)[C@H]2CCC=3C(=O)OCC3)[H]
Synonyms:- 5β,9βH,10α-Labda-8(20),13-dien-16-oic acid, 3α,15,18-trihydroxy-, γ-lactone
- 2(5H)-Furanone, 3-[2-[decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-, [1R-(1α,4aβ,5α,6α,8aα)]-
- 2(5H)-Furanone, 3-[2-[(1R,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-
- Deoxyandrographolide
- 3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone
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Found 8 products.
3-[2-[(1R,4aβ)-2-Methylene-5α-(hydroxymethyl)-5,8aα-dimethyl-6α-hydroxydecalin-1α-yl]ethyl]-2,5-dihydrofuran-2-one
CAS:Formula:C20H30O4Purity:98.0%Color and Shape:SolidMolecular weight:334.449814-Deoxyandrographolide
CAS:14-Deoxyandrographolide has hepatoprotective activity, mediates activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS, may provide a promising approach in the prevention of liver diseases during chronic alcoholism. It desensitizes hepatocytes to TNF-alpha-mediated apoptosis through the release of TNFRSF1A.Formula:C20H30O4Purity:95%~99%Color and Shape:Cryst.Molecular weight:334.45614-Deoxyandrographolide
CAS:14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy.Formula:C20H30O4Purity:99.89% - 99.98%Color and Shape:SolidMolecular weight:334.4514-deoxyandrographolide
CAS:LactoneFormula:C20H30O4Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:334.4514-Deoxyandrographolide
CAS:<p>14-Deoxyandrographolide is a diterpene that has been shown to have hepatoprotective activity. It is also an inhibitor of cyclase and has been shown to be cytotoxic in the range of 10-100 μM, with immunosuppressive effects. 14-Deoxyandrographolide is effective against bowel disease and cancer cell lines by inhibiting the production of tumor necrosis factor-α (TNF-α) and other inflammatory cytokines. 14-Deoxyandrographolide also inhibits the growth of T cells, which may contribute to its anti-inflammatory effects.</p>Formula:C20H30O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:334.45 g/mol14-Deoxyandrographolide
CAS:Controlled ProductFormula:C20H30O4Color and Shape:NeatMolecular weight:334.45
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