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CAS 41850-19-5

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  • 11,17-Dihydroxy-3-oxo-pregn-4-ene-21-carboxylic Acid γ-​Lactone

    CAS:
    <p>Applications 11,17-Dihydroxy-3-oxo-pregn-4-ene-21-carboxylic Acid γ-​Lactone is an intermediate in the synthesis of Des-methylformate Eplerenone (D293955) which is an impurity of Eplerenone (E588775), a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br>References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),<br></p>
    Formula:C22H30O4
    Color and Shape:Neat
    Molecular weight:358.471

    Ref: TR-D883520

    50mg
    1,042.00€