CAS 41945-43-1

1-O-[(2S)-2-(6-methoxynaphthalen-2-yl)propanoyl]-beta-D-glucopyranuronic acid

Description:

1-O-[(2S)-2-(6-methoxynaphthalen-2-yl)propanoyl]-beta-D-glucopyranuronic acid is a complex organic compound characterized by its structural features, which include a glucuronic acid moiety linked to a propanoyl group that is further substituted with a methoxynaphthalene derivative. This compound exhibits properties typical of glycosides, including solubility in polar solvents due to the presence of the glucuronic acid unit, which enhances its hydrophilicity. The methoxynaphthalene portion contributes to its aromatic characteristics, potentially influencing its biological activity and interactions. The stereochemistry indicated by the (2S) configuration suggests specific spatial arrangements that may affect the compound's reactivity and binding properties in biological systems. Additionally, the presence of functional groups such as methoxy and carboxylic acid can impart unique chemical reactivity, making it of interest in various fields, including medicinal chemistry and biochemistry. Overall, this compound's structural complexity and functional diversity suggest potential applications in drug development and therapeutic research.

Formula: C₂₀H₂₂O₉

InChI: InChI=1/C20H22O9/c1-9(10-3-4-12-8-13(27-2)6-5-11(12)7-10)19(26)29-20-16(23)14(21)15(22)17(28-20)18(24)25/h3-9,14-17,20-23H,1-2H3,(H,24,25)/t9-,14-,15-,16+,17-,20-/m0/s1

Naproxen-acyl-β-D-glucuronide

CAS: 41945-43-1

Naproxen-acyl-β-D-glucuronide

Formula: H₂

Purity: >98%

Color and Shape: white amorphous solid

Molecular weight: 406.38g/mol

Ref: 54-BICL4179

Naproxen Acyl Glucuronide

CAS: 41945-43-1

Formula: C₂₀H₂₂O₉

Color and Shape: White To Off-White Solid

Molecular weight: 406.39

Ref: 4Z-N-232

Naproxen Impurity 1 Sodium Salt

CAS: 41945-43-1

Formula: C₁₈H₂₁O₄·Na

Color and Shape: Yellow Solid

Molecular weight: 301.36 22.99

Ref: 4Z-N-2322

(S)-Naproxen acyl-b-D-glucuronide

CAS: 41945-43-1

Ref: 7W-GC3957

(S)-Naproxen Acyl-beta-D-glucuronide

CAS: 41945-43-1

Applications A metabolite of Naproxen.
References Boynton, C., et al.: J. Clin. Pharmacol., 28, 512 (1988), Jin, C., et al.: J. Pharmacol. Exp. Ther., 264, 475 (1993),King, C., et al.: Toxicol. Sci., 61, 49 (2001), Aresta, A., et al.: J. Pharm. Biomed. Anal., 39, 643 (2005),

Formula: C₂₀H₂₂O₉

Color and Shape: Neat

Molecular weight: 406.38

Ref: TR-N377530

(S)-Naproxen acyl-b-D-glucuronide

CAS: 41945-43-1

Naproxen is a non-steroidal anti-inflammatory drug (NSAID) that is used to relieve pain and reduce inflammation. The NSAIDs are metabolized in the liver by oxidation, reduction, hydrolysis, or conjugation with glucuronic acid. Naproxen undergoes a number of metabolic transformations including fragmentation, which can be detected using an MS/MS analyzer. Naproxen acyl-b-D-glucuronide is an oxidative metabolite of naproxen that has been shown to have high uptake into mammalian cells and bioconcentrates in fish. This metabolite has also been shown to be metabolized in the liver by conjugation with glucuronic acid.

Formula: C₂₀H₂₂O₉

Purity: Min. 95%

Molecular weight: 406.38 g/mol

Ref: 3D-MN07309

Naproxen glucuronide

CAS: 41945-43-1

Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.

Formula: C₂₀H₂₂O₉

Color and Shape: Solid

Molecular weight: 406.38

Ref: TM-T69267

Naproxen Acyl Glucuronide

CAS: 41945-43-1

Formula: C₂₀H₂₂O₉

Molecular weight: 406.39

Ref: ST-EA-CP-N2044