CAS 42002-05-1

N-[(1,1-Dimethylethoxy)carbonyl]-L-histidine hydrazide

Description:

N-[(1,1-Dimethylethoxy)carbonyl]-L-histidine hydrazide is a chemical compound characterized by its unique structure, which includes a histidine moiety linked to a hydrazide functional group. This compound features a dimethylethoxycarbonyl protecting group, which is commonly used in organic synthesis to protect amine functionalities during chemical reactions. The presence of the hydrazide group suggests potential reactivity, particularly in forming hydrazones or undergoing condensation reactions. The compound is likely to exhibit solubility in polar solvents due to the presence of the hydrophilic histidine side chain, while the dimethylethoxy group may impart some hydrophobic characteristics. Its applications may extend to peptide synthesis, medicinal chemistry, or as an intermediate in the preparation of more complex molecules. As with many chemical substances, safety precautions should be observed when handling this compound, including the use of appropriate personal protective equipment and adherence to safety data sheet guidelines.

Formula: C₁₁H₁₉N₅O₃

InChI: InChI=1S/C11H19N5O3/c1-11(2,3)19-10(18)15-8(9(17)16-12)4-7-5-13-6-14-7/h5-6,8H,4,12H2,1-3H3,(H,13,14)(H,15,18)(H,16,17)/t8-/m0/s1

InChI key: InChIKey=IIAZPXGGUWPKRC-QMMMGPOBSA-N

SMILES: [C@@H](CC1=CN=CN1)(NC(OC(C)(C)C)=O)C(NN)=O

Synonyms:

• <span class="text-smallcaps">L</span>-Histidine, N-[(1,1-dimethylethoxy)carbonyl]-, hydrazide
• Boc-His-NHNH
• Boc-His-NHNH2
• Boc-L-histidine hydrazide
• Histidine, N-carboxy-, N-tert-butyl ester, hydrazide, <span class="text-smallcaps">L</span>-
• N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-histidine hydrazide
• tert-butyl [2-hydrazino-1-(1H-imidazol-5-ylmethyl)-2-oxoethyl]carbamate (non-preferred name)
• L-Histidine, N-[(1,1-dimethylethoxy)carbonyl]-, hydrazide
• N-[(1,1-Dimethylethoxy)carbonyl]-L-histidine hydrazide
• Histidine, N-carboxy-, N-tert-butyl ester, hydrazide, L-