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CAS 42017-89-0

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Fenofibric acid

Description:
Fenofibric acid is a synthetic compound primarily used as a lipid-regulating agent, particularly in the treatment of dyslipidemia. It is the active metabolite of fenofibrate and belongs to the class of fibrates, which are known to lower triglyceride levels and increase high-density lipoprotein (HDL) cholesterol. The chemical structure of fenofibric acid features a phenolic group and a carboxylic acid, contributing to its solubility and biological activity. It is typically administered in oral form and is well-absorbed in the gastrointestinal tract. The pharmacological action of fenofibric acid involves the activation of peroxisome proliferator-activated receptors (PPARs), which play a crucial role in lipid metabolism. Common side effects may include gastrointestinal disturbances, muscle pain, and liver enzyme alterations. Fenofibric acid is often used in conjunction with dietary modifications to enhance its lipid-lowering effects. Its safety profile and efficacy have been established through various clinical studies, making it a valuable option in managing cholesterol levels and reducing cardiovascular risk.
Formula:C17H15ClO4
InChI:InChI=1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21)
InChI key:InChIKey=MQOBSOSZFYZQOK-UHFFFAOYSA-N
SMILES:C(=O)(C1=CC=C(OC(C(O)=O)(C)C)C=C1)C2=CC=C(Cl)C=C2
Synonyms:
  • 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid
  • 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-Propanoic acid
  • 2-[4′-(p-Chlorobenzoyl)phenoxy]-2-methylpropionic acid
  • 2-[p-(p-Chlorobenzoyl)phenoxy]-2-methylpropionic acid
  • 2-{4-[(4-Chlorophenyl)Carbonyl]Phenoxy}-2-Methylpropanoate
  • FA
  • FNF acid
  • Fenofibrate Acid
  • Fenofibric acid
  • LF 178 acid
  • See more synonyms
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