CAS 42019-78-3

4-Chloro-4′-hydroxybenzophenone

Description:

4-Chloro-4′-hydroxybenzophenone, with the CAS number 42019-78-3, is an organic compound that belongs to the class of benzophenones. It features a biphenyl structure with a hydroxyl group and a chlorine atom substituted on the aromatic rings. This compound is typically characterized by its solid state at room temperature, exhibiting a crystalline appearance. It is known for its applications in the field of photoprotection, often utilized as a UV filter in sunscreens and cosmetic products due to its ability to absorb ultraviolet light. The presence of the hydroxyl group contributes to its solubility in organic solvents, while the chlorine atom enhances its stability and photoprotective properties. Additionally, 4-Chloro-4′-hydroxybenzophenone may exhibit moderate toxicity, necessitating careful handling and appropriate safety measures during use. Its chemical structure allows for various reactions, making it a valuable intermediate in organic synthesis and materials science.

Formula: C₁₃H₉ClO₂

InChI: InChI=1/C13H9ClO2/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(15)8-4-10/h1-8,15H

InChI key: InChIKey=RUETVLNXAGWCDS-UHFFFAOYSA-N

SMILES: C(=O)(C1=CC=C(Cl)C=C1)C2=CC=C(O)C=C2

Synonyms:

• (4-Chlorophenyl)(4-hydroxyphenyl)-Methanone
• 1-(4-Chlorophenyl)-1-(4-hydroxyphenyl)methanone
• 4-(4-Chlorobenzoyl)phenol
• 4-Chloro-4'-Hydroxy Benzophenone
• 4-Hydroxy-4′-chlorobenzophenone
• 4-p-Chlorobenzoylphenol
• Benzophenone, 4-chloro-4′-hydroxy-
• Methanone, (4-chlorophenyl)(4-hydroxyphenyl)-
• 4-Chloro-4-Hydroxybenzophenone
• 4-hydroxy-4’-chloro-benophenone
• (4-CHLORO-PHENYL)-(4-HYDROXY-PHENYL)-METHANONE
• 4-(4-Chlorobenzoyl)-4-Hydroxypiperidine
• 4,4'-Chlorohydroxybenzophenone
• 4-Chloro-4'-Hydroxybenzophenone 4-Hydroxy-4'-Chlorobenzophenone
• 4-Chloro-4'-hydroxybenzophenon
• 4-CHLORO-4''-HYDROXYBENZOPHENONEFENOFIBRATE
• 8) 4-CHLORO 4-HYDROXY BENZOPHENONE
• 4-CHLORO-4''-HYDROXYBENZOPHENONE=99.0%

4-Chloro-4'-hydroxybenzophenone

CAS: 42019-78-3

Formula: C₁₃H₉ClO₂

Purity: >98.0%(GC)

Color and Shape: White to Brown to Dark green powder to crystal

Molecular weight: 232.66

Ref: 3B-C1155

FENOFIBRATE IMPURITY A CRS

CAS: 42019-78-3

FENOFIBRATE IMPURITY A CRS

Formula: C₁₃H₉ClO₂

Molecular weight: 232.6624

Ref: 41-F0048005

Fenofibrate Related Compound A ((4-Chlorophenyl)(4-hydroxyphenyl)methanone)

CAS: 42019-78-3

Halogenated, sulfonated, nitrated or nitrosated derivatives: chlordecone (iso)

Formula: C₁₃H₉ClO₂

Color and Shape: Beige Solid

Molecular weight: 232.02911

Ref: 45-1269607

4-Chloro-4'-hydroxybenzophenone

CAS: 42019-78-3

4-Chloro-4'-hydroxybenzophenone: a tyrosinase inhibitor and antioxidant, prevents lipid/protein oxidation.

Formula: C₁₃H₉ClO₂

Purity: 99.49%

Color and Shape: Colorless Solid Crystalline

Molecular weight: 232.66

Ref: TM-T1344

4-CHLORO-4'-HYDROXYBENZOPHENONE

CAS: 42019-78-3

Formula: C₁₃H₉ClO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 232.6624

Ref: IN-DA003L5F

4-Chloro-4''-hydroxybenzophenone

CAS: 42019-78-3

Formula: C₁₃H₉ClO₂

Purity: ≥ 98.0%

Color and Shape: White to off-white or pale yellow-brown crystalline powder

Molecular weight: 232.67

Ref: 7W-GK4354

4-Chloro-4'-hydroxybenzophenone

CAS: 42019-78-3

4-Chloro-4'-hydroxybenzophenone

Purity: ≥98%

Molecular weight: 232.66g/mol

Ref: 54-BUP13781

Fenofibrate EP Impurity A (Fenofibrate USP Related Compound A)

CAS: 42019-78-3

Formula: C₁₃H₉ClO₂

Color and Shape: White To Off-White Solid

Molecular weight: 232.66

Ref: 4Z-F-0210

(4-Chlorophenyl)(4-hydroxyphenyl)methanone

CAS: 42019-78-3

(4-Chlorophenyl)(4-hydroxyphenyl)methanone

Purity: 98%

Molecular weight: 232.66g/mol

Ref: 54-OR79835

(4-Chlorophenyl)(4-hydroxyphenyl)methanone

CAS: 42019-78-3

Color and Shape: Neat

Ref: 86-MM0505.01

4-Chloro-4’-hydroxybenzophenone

Controlled Product

CAS: 42019-78-3

Impurity Fenofibrate EP Impurity A; Fenofibrate USP Related Compound A
Applications 4-Chloro-4’-hydroxybenzophenone (Fenofibrate EP Impurity A; Fenofibrate USP Related Compound A) the impurity of Fenofibric acid (42017-89-0), the active metabolite of fenofibrate which increases Apolipoprotein A-I–Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor–dependent manner.
References Barter, P.J.: Arterioscler. Thromb. Vasc. Biol., 25, 1095 (2005)

Formula: C₁₃H₉ClO₂

Color and Shape: Neat

Molecular weight: 232.66

Ref: TR-C366700

Fenofibrate EP Impurity A

CAS: 42019-78-3

Formula: C₁₃H₉ClO₂

Molecular weight: 232.66

Ref: ST-EA-CP-F12001

4-Chloro-4′-hydroxybenzophenone

CAS: 42019-78-3

Formula: C₁₃H₉ClO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 232.66

Ref: 10-F046142

4-Chloro-4'-hydroxybenzophenone

CAS: 42019-78-3

4-Chloro-4'-hydroxybenzophenone is a chemical intermediate that is used to produce p-hydroxybenzoic acid by acylation reaction with hydrochloric acid. The optimal reaction of 4-chloro-4'-hydroxybenzophenone with hydrochloric acid occurs at a temperature of 40 degrees Celsius and an excess of 2 equivalents of hydrochloric acid per equivalent of 4-chloro-4'-hydroxybenzophenone. This chemical intermediate has been shown to be an environmental pollutant, as it reacts in the atmosphere with ozone or other oxidizing agents to form hydrogen chloride and aluminium chloride. The transfer mechanism for this process is not yet well understood, but it may be due to demethylation followed by chlorination.

Formula: C₁₃H₉ClO₂

Purity: Min. 95%

Molecular weight: 232.66 g/mol

Ref: 3D-FC20083