CAS 421-83-0

Trifluoromethanesulfonyl chloride

Description:

Trifluoromethanesulfonyl chloride, with the CAS number 421-83-0, is a chemical compound characterized by its strong electrophilic properties due to the presence of both trifluoromethyl and sulfonyl chloride functional groups. It appears as a colorless to pale yellow liquid and has a pungent odor. This compound is highly reactive and is known for its ability to act as a sulfonylating agent, making it useful in organic synthesis, particularly in the preparation of sulfonamides and other sulfonyl derivatives. Trifluoromethanesulfonyl chloride is soluble in organic solvents but reacts vigorously with water, releasing hydrogen chloride and forming trifluoromethanesulfonic acid. Due to its reactivity, it must be handled with care, as it can cause severe burns and is toxic if inhaled or ingested. Its applications extend to the pharmaceutical industry and materials science, where it serves as a reagent in various chemical transformations. Proper safety measures, including the use of personal protective equipment, are essential when working with this compound.

Formula: CClF₃O₂S

InChI: InChI=1S/CClF3O2S/c2-8(6,7)1(3,4)5

InChI key: InChIKey=GRGCWBWNLSTIEN-UHFFFAOYSA-N

SMILES: C(S(Cl)(=O)=O)(F)(F)F

Synonyms:

• Methanesulfonyl chloride, trifluoro-
• Trifluoro Methanesulfornylchloride
• Trifluoromethanesulphonyl chloride
• Trifluoromethylsulfonyl chloride
• Trifluoromethylsulfuryl chloride
• Triflyl chloride
• Trifluoromethanesulfonyl chloride

Trifluoromethanesulfonyl Chloride

CAS: 421-83-0

Formula: CClF₃O₂S

Purity: >98.0%(GC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 168.51

Ref: 3B-T1027

Trifluoromethanesulfonyl chloride, 98%

CAS: 421-83-0

Ru(II) complex-catalyzed trifluoromethylating agent for aromatics and alkenes. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code o

Formula: CF₃SO₂Cl

Purity: 98%

Color and Shape: Clear or slightly turbid, colorless to yellow, Liquid

Molecular weight: 168.52

Ref: 02-B21774

Trifluoromethanesulphonyl chloride

CAS: 421-83-0

Trifluoromethanesulphonyl chloride

Purity: 97%

Color and Shape: Pale Yellow Liquid

Molecular weight: 168.52g/mol

Ref: 54-PC7430

Trifluoromethanesulfonyl chloride

CAS: 421-83-0

Formula: CClF₃O₂S

Purity: 98.0%

Color and Shape: Liquid

Molecular weight: 168.51

Ref: 10-F019220

Trifluoromethanesulfonyl Chloride

Controlled Product

CAS: 421-83-0

Formula: CClF₃O₂S

Color and Shape: Neat

Molecular weight: 168.52

Ref: TR-T896578

Trifluoromethanesulfonyl chloride

CAS: 421-83-0

Trifluoromethanesulfonyl chloride is a reactive chemical that reacts with nucleophilic groups in biological molecules. It is used for the treatment of infectious diseases and metabolic disorders. Trifluoromethanesulfonyl chloride has been shown to have receptor activity against various microorganisms, including resistant strains. Structural analysis has shown that the active form of trifluoromethanesulfonyl chloride binds to malonic acid and other coumarin derivatives. This binding prevents the formation of hydrogen bonds, which would otherwise stabilize the molecule, leading to its degradation. Trifluoromethanesulfonyl chloride also reacts with magnesium salt to produce trifluoroacetic acid, which is an organic solvent that can be used as a reaction medium or a reagent in organic synthesis.

Formula: CClF₃O₂S

Purity: Min. 95%

Molecular weight: 168.52 g/mol

Ref: 3D-FT03446

Trifluoromethanesulfonyl chloride

CAS: 421-83-0

Formula: CClF₃O₂S

Purity: 98%

Color and Shape: Liquid

Molecular weight: 168.5227

Ref: IN-DA003V2I