CAS 421-85-2

1,1,1-Trifluoromethanesulfonamide

Description:

1,1,1-Trifluoromethanesulfonamide, with the CAS number 421-85-2, is a chemical compound characterized by its trifluoromethyl and sulfonamide functional groups. It appears as a colorless to pale yellow liquid or solid, depending on temperature and purity. This compound is known for its high stability and low volatility, making it useful in various chemical applications, particularly in the synthesis of pharmaceuticals and agrochemicals. Its trifluoromethyl group imparts unique electronic properties, enhancing its reactivity in nucleophilic substitution reactions. Additionally, 1,1,1-Trifluoromethanesulfonamide exhibits good solubility in polar solvents, which facilitates its use in diverse chemical environments. However, it is important to handle this substance with care, as it may pose health risks upon exposure, including potential toxicity. Proper safety measures, including the use of personal protective equipment, are recommended when working with this compound in laboratory settings. Overall, its distinctive chemical properties make it a valuable reagent in organic synthesis and industrial applications.

Formula: CH₂F₃NO₂S

InChI: InChI=1S/CH2F3NO2S/c2-1(3,4)8(5,6)7/h(H2,5,6,7)

InChI key: InChIKey=KAKQVSNHTBLJCH-UHFFFAOYSA-N

SMILES: C(S(N)(=O)=O)(F)(F)F

Synonyms:

• 1,1,1-Trifluoromethanesulfonamide
• Methanesulfonamide, 1,1,1-trifluoro-
• Trifluoromethanesulfonamide
• Trifluoromethylsulfonamide

Trifluoromethanesulfonamide

CAS: 421-85-2

Formula: CH₂F₃NO₂S

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 149.09

Ref: 3B-T1290

Trifluoromethanesulfonamide

CAS: 421-85-2

Formula: CH₂F₃NO₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 149.0923

Ref: IN-DA003V2G

Trifluoromethanesulfonamide

CAS: 421-85-2

Formula: CH₂F₃NO₂S

Purity: ≥ 98.0%

Color and Shape: White to off-white or light-yellow crystalline powder

Molecular weight: 149.09

Ref: 7W-GL9311

Trifluoromethanesulphonamide

CAS: 421-85-2

Trifluoromethanesulphonamide

Formula: CH₂F₃NO₂S

Purity: 98%

Color and Shape: white to off-white crystalline solid

Molecular weight: 149.09g/mol

Ref: 54-PC7406

Trifluoromethanesulfonamide

CAS: 421-85-2

Trifluoromethanesulfonamide is a strong acid that has been shown to inhibit the proteolytic activity of human secretase. It binds to a specific site on the enzyme and prevents it from cleaving the substrate. This inhibition slows down the progression of Alzheimer's disease, Parkinson's disease, and other related disorders. Trifluoromethanesulfonamide has also been shown to bind to metal hydroxides, such as iron hydroxide, which may be due to its ability to form hydrogen bonds with these metals. Structural analysis reveals that trifluoromethanesulfonamide contains a pyrazole ring and two chlorine atoms, one in the para position and one in the meta position.

Formula: CH₂F₃NO₂S

Color and Shape: Powder

Molecular weight: 149.09 g/mol

Ref: 3D-FT71515

Trifluoromethanesulfonamide

CAS: 421-85-2

Formula: CH₂F₃NO₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 149.09

Ref: 10-F007525

Trifluoromethylsulfonamide

Controlled Product

CAS: 421-85-2

Formula: CH₂F₃NO₂S

Color and Shape: Neat

Molecular weight: 149.09

Ref: TR-T792410

Trifluoromethanesulfonamide, 96%

CAS: 421-85-2

Trifluoromethanesulfonamide is used as an intermediate in synthetic chemistry. It is used in the preparation of specific inhibitors of mammalian secreted phospholipases A2. It is also involved in the synthesis of ecicosanoids. This Thermo Scientific Chemicals brand product was originally part of the

Formula: CF₃SO₂NH₂

Purity: 96%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream

Molecular weight: 149.09

Ref: 02-B22112