CAS 42123-33-1

3-Hydroxy-2-nitrobenzaldehyde

Description:

3-Hydroxy-2-nitrobenzaldehyde, with the CAS number 42123-33-1, is an organic compound characterized by the presence of both a hydroxyl group (-OH) and a nitro group (-NO2) on a benzaldehyde structure. This compound features a benzene ring with a formyl group (-CHO) at one position, a hydroxyl group at the meta position, and a nitro group at the ortho position relative to the formyl group. It typically appears as a yellow to orange crystalline solid and is soluble in organic solvents. The presence of the hydroxyl and nitro groups contributes to its reactivity, making it a useful intermediate in organic synthesis, particularly in the preparation of dyes, pharmaceuticals, and agrochemicals. Additionally, the compound may exhibit various functional properties, including potential antioxidant activity and biological significance, which can be explored in medicinal chemistry. Proper handling and storage are essential due to its potential toxicity and reactivity, particularly in the presence of strong reducing agents or bases.

Formula: C₇H₅NO₄

InChI: InChI=1S/C7H5NO4/c9-4-5-2-1-3-6(10)7(5)8(11)12/h1-4,10H

InChI key: InChIKey=ADSNHKTXYJZXDF-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C(C=O)C=CC=C1O

Synonyms:

• 3-Hydroxy-2-nitrobenzaldehyde
• Benzaldehyde, 3-hydroxy-2-nitro-
• 2-Nitro-3-hydroxybenzaldehyde

3-Hydroxy-2-nitrobenzaldehyde

CAS: 42123-33-1

Formula: C₇H₅NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 167.1189

Ref: IN-DA00CIUF

3-Hydroxy-2-nitrobenzaldehyde

CAS: 42123-33-1

3-Hydroxy-2-nitrobenzaldehyde

Purity: 99%

Molecular weight: 167.12g/mol

Ref: 54-OR510181

3-Hydroxy-2-nitrobenzaldehyde

CAS: 42123-33-1

Purity: 97%

Molecular weight: 167.1199951

Ref: 10-F605964

3-Hydroxy-2-nitrobenzaldehyde

CAS: 42123-33-1

3-Hydroxy-2-nitrobenzaldehyde (3HNB) is a potent inhibitor of glucose uptake. This compound inhibits the activity of glucose transporter 2 (GLUT2), which is responsible for transporting glucose across the cell membrane into the cell. In addition, 3HNB has been shown to inhibit the activity of other glucose transporters and enzymes involved in glycolysis and gluconeogenesis, leading to reduced rates of glucose production and increased rates of glucose consumption. The hypoglycemic effect of 3HNB is due to its inhibition of key enzymes involved in carbohydrate metabolism, as well as its ability to block GLUT2 from transporting glucose into cells. It has also been shown that 3HNB can cause weight loss by decreasing appetite and increasing energy expenditure in mice fed high fat diets.

Formula: C₇H₅NO₄

Purity: Min. 95%

Molecular weight: 167.12 g/mol

Ref: 3D-SBA12333