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CAS 4213-45-0

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Quinacrine mustard

Description:
Quinacrine mustard, with the CAS number 4213-45-0, is a synthetic compound that belongs to the class of alkylating agents, specifically a mustard derivative of quinacrine. It exhibits characteristics typical of mustard agents, including the ability to form covalent bonds with nucleophilic sites in DNA, leading to potential cytotoxic effects. Quinacrine mustard is known for its antitumor properties and has been investigated for its potential use in cancer therapy due to its ability to interfere with DNA replication and transcription. The compound is typically a yellow crystalline solid and is soluble in organic solvents, but its solubility in water is limited. Its mechanism of action involves the alkylation of DNA, which can result in cross-linking and subsequent cell death, making it a subject of interest in both medicinal chemistry and cancer research. However, like many alkylating agents, it may also exhibit toxicity and side effects, necessitating careful handling and consideration in therapeutic applications.
Formula:C23H28Cl3N3O·2ClH
InChI:InChI=1S/C23H28Cl3N3O.2ClH/c1-16(4-3-11-29(12-9-24)13-10-25)27-23-19-7-5-17(26)14-22(19)28-21-8-6-18(30-2)15-20(21)23;;/h5-8,14-16H,3-4,9-13H2,1-2H3,(H,27,28);2*1H
InChI key:InChIKey=JETDZFFCRPFPDH-UHFFFAOYSA-N
SMILES:N(C(CCCN(CCCl)CCCl)C)C=1C2=C(N=C3C1C=CC(Cl)=C3)C=CC(OC)=C2.Cl
Synonyms:
  • 1,4-Pentanediamine, N',N'-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-9-acridinyl)-, 2HCl
  • 1,4-Pentanediamine, N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-9-acridinyl)-, dihydrochloride
  • 1,4-Pentanediamine, N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-9-acridinyl)-, hydrochloride (1:2)
  • 1,4-Pentanediamine, N<sup>1</sup>,N<sup>1</sup>-bis(2-chloroethyl)-N<sup>4</sup>-(6-chloro-2-methoxy-9-acridinyl)-, dihydrochloride
  • 1,4-Pentanediamine, N<sup>1</sup>,N<sup>1</sup>-bis(2-chloroethyl)-N<sup>4</sup>-(6-chloro-2-methoxy-9-acridinyl)-, hydrochloride (1:2)
  • 2-Methoxy-6-chloro-9-(3-(ethyl-2-chloroethyl)aminopropylamino)acridine dihydrochloride
  • 2-Methoxy-6-chloro-9-(4-bis(2-chloroethyl)amino-1-methylbutylamino)acridine dihydrochloride
  • 2-Methoxy-6-chloro-9-[4-bis[2-chloroethyl]amino-1-methylbutyl amino)acridine dihydrochloride
  • 9-(4-Bis(2-chloroethyl)amino-1-methylbutylamino)-6-chloro-2-methoxyacridine dihydrochloride
  • Acridine, 9-(4-bis(2-chloroethyl)amino-1-methylbutylamino)-6-chloro-2-methoxy-, dihydrochloride
  • See more synonyms
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