CAS 42203-78-1

(±)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride

Description:

(±)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride, commonly referred to as DOI, is a synthetic compound belonging to the class of phenethylamines and is structurally related to the hallucinogenic compound mescaline. It features a methoxy group at the 2 and 5 positions and an iodine atom at the 4 position of the phenyl ring, contributing to its unique pharmacological properties. DOI acts primarily as a serotonin receptor agonist, particularly at the 5-HT2A receptor, which is implicated in its psychedelic effects. The hydrochloride salt form enhances its solubility in water, making it suitable for various research applications. DOI is known for its potency and long duration of action, often leading to prolonged effects compared to other hallucinogens. As a research chemical, it is not approved for medical use and is subject to regulatory controls in many jurisdictions. Safety and toxicity profiles are still under investigation, and its use should be approached with caution due to potential psychological effects and the risk of adverse reactions.

Formula: C₁₁H₁₆INO₂·ClH

InChI: InChI=1S/C11H16INO2.ClH/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2;/h5-7H,4,13H2,1-3H3;1H

InChI key: InChIKey=QVFDMWGKHUFODK-UHFFFAOYSA-N

SMILES: C(C(C)N)C1=C(OC)C=C(I)C(OC)=C1.Cl

Synonyms:

• (+/-)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride
• (+/-)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride
• (±)-1-(4-Iodo-2,5-dimethoxyphenyl)-2-aminopropane hydrochloride
• 2-Amino-1-(2,5-Dimethoxy-4-iodophenyl)propane hydrochloride
• Benzeneethanamine, 4-iodo-2,5-dimethoxy-alpha-methyl-, hydrochloride (1:1)
• Benzeneethanamine, 4-iodo-2,5-dimethoxy-α-methyl-, hydrochloride
• Benzeneethanamine, 4-iodo-2,5-dimethoxy-α-methyl-, hydrochloride (1:1)
• DOI
• 1-(4-Iodo-2,5-dimethoxyphenyl)propan-2-amine hydrochloride (1:1)

d,l-DOI.HCl

Controlled Product

CAS: 42203-78-1

Color and Shape: Neat

Ref: LP-DOI-1586-HC-10

d,l-DOI.HCl, 1mg/ml in Methanol (as free base)

Controlled Product

CAS: 42203-78-1

Color and Shape: Single Solution

Ref: LP-DOI-1586-HC-1LM

DOI Hydrochloride

Controlled Product

CAS: 42203-78-1

Formula: C₁₁H₁₆INO₂·ClH

Color and Shape: Off-White

Molecular weight: 357.62

Ref: TR-D535763

(±)-DOI Hydrochloride

Controlled Product

CAS: 42203-78-1

(±)-DoiHydrochloride is a serotonergic drug that belongs to the group of serotonin reuptake inhibitors. It affects the serotonergic system by inhibiting serotonin reuptake, which leads to increased synaptic concentrations of serotonin. This in turn activates signal pathways and increases levels of dopamine, norepinephrine, and epinephrine. (±)-DoiHydrochloride has antioxidative properties and can be used for the treatment of chronic schizophrenia. It was shown to be effective in patients with atrial fibrillation who were not responding well to other treatments.

Formula: C₁₁H₁₆INO₂•HCl

Purity: Min. 95%

Molecular weight: 357.62 g/mol

Ref: 3D-FD152269