CAS 4229-38-3

2-acetamido-1-amino-1,2-dideoxy-B-D-*glucopyranos

Description:

2-Acetamido-1-amino-1,2-dideoxy-β-D-glucopyranose, commonly referred to as a derivative of glucosamine, is a monosaccharide characterized by the presence of both amino and acetamido functional groups. This compound features a pyranose ring structure, which is typical of many carbohydrates, and is specifically a dideoxy sugar, indicating that it lacks hydroxyl groups at certain positions on the sugar ring. The acetamido group contributes to its solubility in water and its biological activity, making it relevant in various biochemical applications. The presence of amino groups allows for potential interactions in biological systems, including enzyme-substrate interactions and participation in glycosylation processes. This compound is often studied for its role in the synthesis of glycosaminoglycans and other polysaccharides, as well as its potential therapeutic applications in treating conditions related to inflammation and joint health. Its CAS number, 4229-38-3, is a unique identifier that facilitates its identification in chemical databases and literature.

Formula: C₈H₁₆N₂O₅

InChI: InChI=1/C8H16N2O5/c1-3(12)10-5-7(14)6(13)4(2-11)15-8(5)9/h4-8,11,13-14H,2,9H2,1H3,(H,10,12)/t4-,5+,6+,7+,8+/m0/s1

Synonyms:

• N-[(2R,3R,4R,5S,6S)-2-amino-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-3-yl]acetamide

2-Acetamido-2-deoxy-b-D-glucosylamine

CAS: 4229-38-3

Formula: C₈H₁₆N₂O₅

Purity: ≥ 95.0%

Color and Shape: Off-white to light yellow crystalline powder

Molecular weight: 220.22

Ref: 7W-GC6984

2-Acetamido-1-amino-1,2-dideoxy-β-D-glucopyranose

CAS: 4229-38-3

2-Acetamido-1-amino-1,2-dideoxy-β-D-glucopyranose

Formula: C₈H₁₆N₂O₅

Purity: 95%

Color and Shape: solid

Molecular weight: 220.22g/mol

Ref: 54-OR5825T

2-Acetamido-2-deoxy-b-D-glucopyranosyl amine

CAS: 4229-38-3

2-Acetamido-2-deoxy-b-D-glucopyranosyl amine is a synthetic molecule that has shown to be an effective therapeutic agent for the treatment of juvenile idiopathic arthritis. It binds to the surface of cells and activates the immune system by generating antibodies against the disease. This drug has been shown to reduce disease activity in patients with juvenile idiopathic arthritis, as well as improve quality of life. 2-Acetamido-2-deoxy-b-D-glucopyranosyl amine is being developed for use in other autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, and psoriasis.

Formula: C₈H₁₆N₂O₅

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 220.22 g/mol

Ref: 3D-MA05135

2-Acetamido-2-deoxy-β-D-glucopyranosyl amine

CAS: 4229-38-3

2-Acetamido-2-deoxy-beta-D-glucopyranosyl amine (A2DG) is a diagnostic marker for juvenile idiopathic polyarteritis nodosa. This molecule is an intermediate in the synthesis of the carbohydrate, heparin. The A2DG assay measures concentrations of this metabolite in plasma samples and can be used to diagnose vasculitis and other inflammatory diseases. Novartis has developed a metabolite profiling technique that uses mass spectrometry to identify molecules present in cell culture or plasma samples. This technique has been used to measure levels of A2DG metabolites in patients with vasculitis, including juvenile idiopathic polyarteritis nodosa.

Formula: C₈H₁₆N₂O₅

Purity: Min. 95.0 Area-%

Molecular weight: 220.22 g/mol

Ref: 3D-W-202730

N-((2R,3R,4R,5S,6R)-2-amino-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide

CAS: 4229-38-3

Purity: 98%

Molecular weight: 220.2250061

Ref: 10-F773797