CAS 42348-86-7

5-Chloro-1-indanone

Description:

5-Chloro-1-indanone is an organic compound characterized by its indanone structure, which features a fused benzene and cyclopentanone ring system. The presence of a chlorine atom at the 5-position of the indanone ring contributes to its reactivity and potential applications in organic synthesis. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its purity and form. It is known for its role as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. The compound exhibits moderate solubility in organic solvents, while its solubility in water is limited. 5-Chloro-1-indanone may undergo typical reactions associated with carbonyl compounds, such as nucleophilic addition and condensation reactions. Safety data indicates that, like many chlorinated compounds, it should be handled with care due to potential toxicity and environmental concerns. Proper storage and handling protocols are essential to ensure safety in laboratory and industrial settings.

Formula: C₉H₇ClO

InChI: InChI=1S/C9H7ClO/c10-7-2-3-8-6(5-7)1-4-9(8)11/h2-3,5H,1,4H2

InChI key: InChIKey=MEDSHTHCZIOVPU-UHFFFAOYSA-N

SMILES: O=C1C=2C(CC1)=CC(Cl)=CC2

Synonyms:

• 1-Indanone, 5-chloro-
• 1H-Inden-1-one, 5-chloro-2,3-dihydro-
• 5-Chloro Indanone
• 5-Chloro-1-indanone,99%
• 5-Chloro-2,3-Dihydroinden-1-One
• 5-Chloro-2,3-dihydro-1H-inden-1-one
• 5-Chloroindan-1-Indanone
• 5-Chloroindan-1-One
• 5-Chloro-1-indanone

5-Chloro-1-Indanone

CAS: 42348-86-7

Formula: C₉H₇ClO

Purity: 97%

Color and Shape: Solid

Molecular weight: 166.6043

Ref: IN-DA00348P

5-Chloroindan-1-one

CAS: 42348-86-7

5-Chloroindan-1-one

Formula: C₉H₇ClO

Purity: ≥95%

Color and Shape: pale yellow solid

Molecular weight: 166.60g/mol

Ref: 54-OR0020

5-Chloro-1-indanone

CAS: 42348-86-7

Formula: C₉H₇ClO

Molecular weight: 166.61

Ref: 7W-GK9755

5-Chloro-1-indanone

CAS: 42348-86-7

Formula: C₉H₇ClO

Purity: >97.0%(GC)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 166.60

Ref: 3B-C1644

5-Chloro-1-Indanone

Controlled Product

CAS: 42348-86-7

Applications 5-Chloro-1-Indanone is used as a reagent in the synthesis of novel tricyclic pyrazoles as CB1 and CB2 cannabinoid receptors. Also used in he synthesis of heteroarylmethylidene cubstituted compounds as selective inhibitors of aldosterone synthase.
References Ulmschneider, S. et al.: J. Med. Chem., 48, 1563 (2005); Ulmschneider, S. et al.: J. Med. Chem., 48, 1563 (2005);

Formula: C₉H₇ClO

Color and Shape: Neat

Molecular weight: 166.6

Ref: TR-C367235

5-Chloro-1-indanone

CAS: 42348-86-7

5-Chloro-1-indanone is an organic molecule with a reactive functional group that can react with other molecules. The most common reaction is the Friedel-Crafts reaction, which is used to make alkenes from aldehydes and aluminum chloride. 5-Chloro-1-indanone is also used in the acylation reaction, which involves the transfer of an acyl group to a molecule. This process has many applications, such as synthesis of pesticides and pharmaceuticals, and can be used to produce low energy chlorine gas. Panc-1 cells are often used in anticancer research because they are sensitive to carcinogens. 5-Chloro-1-indanone was shown to inhibit cell growth in these cells by reacting with hydrogen chloride (HCl) in water to form 5-(chloromethyl)-1H indene and hydrochloric acid (HCl).

Formula: C₉H₇ClO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 166.6 g/mol

Ref: 3D-FC00938

5-Chloro-1-indanone

CAS: 42348-86-7

Formula: C₉H₇ClO

Purity: 97%

Color and Shape: Solid

Molecular weight: 166.6

Ref: 10-F001148