CAS 4242-18-6

5,6,7,8-Tetrahydro-1-naphthalenecarboxylic acid

Description:

5,6,7,8-Tetrahydro-1-naphthalenecarboxylic acid is an organic compound characterized by its bicyclic structure, which consists of a naphthalene ring system that has undergone partial hydrogenation. This results in a saturated, tetrahydro configuration, contributing to its unique chemical properties. The presence of a carboxylic acid functional group (-COOH) enhances its acidity and solubility in polar solvents, making it reactive in various chemical reactions, such as esterification and amidation. The compound is typically a white to off-white solid at room temperature and may exhibit moderate stability under standard conditions. Its molecular structure allows for potential applications in pharmaceuticals, agrochemicals, and as an intermediate in organic synthesis. Additionally, the compound's stereochemistry can influence its biological activity, making it of interest in medicinal chemistry. Safety data should be consulted for handling and storage, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₁₁H₁₂O₂

InChI: InChI=1S/C11H12O2/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10/h3,5,7H,1-2,4,6H2,(H,12,13)

InChI key: InChIKey=GCFQXKYHWFWGSB-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C2C(=CC=C1)CCCC2

Synonyms:

• 1-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-
• 1-Naphthoic acid, 5,6,7,8-tetrahydro-
• 5,6,7,8-Tetrahedro-1-Naphthoic Acid
• 5,6,7,8-Tetrahydro-1-Naphthalenecarboxylic Acid
• 5,6,7,8-Tetrahydro-1-naphthoic acid
• 5,6,7,8-Tetrahydronaphthalen-1-carboxylic acid
• NSC 44874

5,6,7,8-Tetrahydronaphthalene-1-carboxylic Acid

CAS: 4242-18-6

Formula: C₁₁H₁₂O₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 176.22

Ref: 3B-T2672

5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid

CAS: 4242-18-6

Formula: C₁₁H₁₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 176.2118

Ref: IN-DA003M9B

5,6,7,8-Tetrahydronaphthalene-1-carboxylic Acid

CAS: 4242-18-6

Color and Shape: Neat

Ref: 86-MM3779.08

5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid

CAS: 4242-18-6

5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid

Purity: 98%

Molecular weight: 176.21g/mol

Ref: 54-OR912055

5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid

CAS: 4242-18-6

Formula: C₁₁H₁₂O₂

Purity: 98%

Color and Shape: White to almost white powder

Molecular weight: 176.215

Ref: 10-F066524

5,6,7,8-Tetrahydronaphthalene-1-carboxylic Acid

Controlled Product

CAS: 4242-18-6

Applications An intermediate used for the preparation of the therapeutically useful antiemetic agent Palonosetron (P165805). hydrochloride.
References Adams, J., et al.: Cancer Cell, 5, 417 (2004), Zhu, Y., et al.: J. Med. Chem., 52, 4192 (2009), Zhu, Y.-Q., et al.: J. Med. Chem., 53, 8619 (2010),

Formula: C₁₁H₁₂O₂

Color and Shape: Neat

Molecular weight: 176.21

Ref: TR-T294100

5,6,7,8-Tetrahydro-1-naphthoic acid

CAS: 4242-18-6

5,6,7,8-Tetrahydro-1-naphthoic acid is a synthetic organic compound that is used to make dyes and paints. It has toxic properties and can cause irritation of the skin or lungs. The mechanism of its toxicity is not known, but it may be due to the formation of reactive oxygen species in the body or the inhibition of monoamine oxidase. 5,6,7,8-Tetrahydro-1-naphthoic acid exhibits dose-dependent toxicity with increasing doses resulting in more severe reactions. It also has a high potential for long term carcinogenicity.

Formula: C₁₁H₁₂O₂

Purity: Min. 95%

Molecular weight: 176.21 g/mol

Ref: 3D-FT04392