CAS 42467-24-3

Adenosine 5'-(tetrahydrogen triphosphate), 2-methyl-

Description:

Adenosine 5'-(tetrahydrogen triphosphate), 2-methyl-, commonly referred to as a modified form of ATP, is a nucleotide that plays a crucial role in cellular energy transfer. This compound features an adenosine moiety linked to a triphosphate group, which is essential for energy metabolism in biological systems. The presence of the 2-methyl group indicates a structural modification that may influence its biochemical properties and interactions. Typically, such modifications can affect the stability, reactivity, and binding affinity of the molecule to various enzymes and receptors. The triphosphate group is characterized by high-energy phosphate bonds, which are hydrolyzed to release energy for cellular processes. This compound is soluble in water and exhibits a polar nature due to its phosphate groups, making it readily available for enzymatic reactions in the aqueous environment of cells. Its CAS number, 42467-24-3, allows for precise identification in chemical databases, facilitating research and application in biochemistry and molecular biology.

Formula: C₁₁H₁₈N₅O₁₃P₃

Synonyms:

• Adenosine 5'-(tetrahydrogen triphosphate), 2-methyl-
• 2-Methyladenosine-5'-triphosphate
• ((2R,3S,4R,5R)-5-(6-Amino-2-methyl-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate

2-Methyladenosine-5'-triphosphate

CAS: 42467-24-3

2-Methyladenosine-5'-triphosphate (2-MeATP) is an inhibitor of the purinergic receptor P2X. It is a competitive antagonist of ATP at the P2X receptor, blocking ATP binding and inhibiting ATP-mediated signal transduction. 2-MeATP has been shown to inhibit angiotensin-mediated hyperpolarization in wild type and mutant strains of M. smegmatis, as well as m. tuberculosis perfusion in mesenteric lymph nodes and vasoconstriction in wildtype and mutant strains of AT1 receptors.

Formula: C₁₁H₁₈N₅O₁₃P₃

Purity: Min. 95%

Molecular weight: 521.21 g/mol

Ref: 3D-NM167712