CAS 42492-65-9

N-[(1,1-Dimethylethoxy)carbonyl]glycine-2,2-d₂

Description:

N-[(1,1-Dimethylethoxy)carbonyl]glycine-2,2-d2, with the CAS number 42492-65-9, is a deuterated derivative of glycine, an amino acid. This compound features a carbonyl group attached to the nitrogen of the glycine structure, which is further substituted with a 1,1-dimethylethoxy group. The presence of deuterium (d2) indicates that two hydrogen atoms in the glycine backbone have been replaced with deuterium isotopes, which can be useful in various applications, including NMR spectroscopy and metabolic studies. The 1,1-dimethylethoxy group enhances the lipophilicity and steric properties of the molecule, potentially influencing its reactivity and solubility. This compound is typically used in research settings, particularly in studies involving isotopic labeling and the synthesis of more complex molecules. Its unique structure allows for specific interactions in biochemical pathways, making it a valuable tool in organic and medicinal chemistry.

Formula: C₇H₁₁D₂NO₄

InChI: InChI=1S/C7H13NO4/c1-7(2,3)12-6(11)8-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)/i4D2

InChI key: InChIKey=VRPJIFMKZZEXLR-APZFVMQVSA-N

SMILES: O(C(NC(C(O)=O)([2H])[2H])=O)C(C)(C)C

Synonyms:

• 2-(tert-Butoxycarbonylamino)-2,2-dideuterio-acetic acid
• N-[(1,1-Dimethylethoxy)carbonyl]glycine-2,2-d2
• Glycine-2,2-d2, N-[(1,1-dimethylethoxy)carbonyl]-
• N-(tert-Butoxycarbonyl)glycine-2,2-d2, Glycine-2,2-d2, N-t-Boc derivative
• GLYCINE-2,2-D2-N-T-BOC
• Glycine-2,2-d2, N-t-Boc derivative
• BOC-GLY-OH-2,2-D2
• Glycine-d2-N-t-BOC
• N-(tert-Butoxycarbonyl)glycine-2,2-d2

Boc-Glycine-D2

CAS: 42492-65-9

Boc-Glycine-D2

Purity: 98%

Molecular weight: 177.19g/mol

Ref: 54-DE2169

Glycine-2,2-d2-N-t-BOC

CAS: 42492-65-9

Formula: HOOCCD₂NHtBOC

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 177.20

Ref: 3U-D2123

N-[(1,1-Dimethylethoxy)carbonyl]glycine-2,2-d2

Controlled Product

CAS: 42492-65-9

Applications N-[(1,1-Dimethylethoxy)carbonyl]glycine-2,2-d2 is a reagent in the identification of a ERα17p, a peptide reproducing the hinge region of the estrogen receptor α, which exerts pharmacological efffects in breast cancer cells.
References Byrne, C., et al.: Steroids, 77, 979-987 (2012)

Formula: C₇D₂H₁₁NO₄

Color and Shape: Neat

Molecular weight: 177.19

Ref: TR-D472928