2-Piperidinone, 1-benzoyl- (CAS 4252-56-6) is a chemical compound characterized by its piperidinone structure, which features a six-membered ring containing a nitrogen atom and a carbonyl group. This compound is typically a white to off-white solid and is soluble in organic solvents such as ethanol and acetone, but may have limited solubility in water due to its hydrophobic benzoyl group. It exhibits properties typical of both amides and ketones, making it a versatile intermediate in organic synthesis. The presence of the benzoyl group enhances its reactivity, allowing it to participate in various chemical reactions, including acylation and nucleophilic substitutions. Additionally, 2-Piperidinone, 1-benzoyl- may have applications in pharmaceuticals and agrochemicals, serving as a building block for the synthesis of more complex molecules. As with many organic compounds, handling should be done with care, following appropriate safety protocols to mitigate any potential health risks associated with exposure.

2-Piperidinone, 1-benzoyl-

4252-56-6: 2-Piperidinone, 1-benzoyl- (CAS 4252-56-6) is a chemical compound characterized by its piperidinone structure, which features a six-membered ring containing a nitrogen atom and a carbonyl group. This compound is typically a white to off-white solid and is soluble in organic solvents such as ethanol and acetone, but may have limited solubility in water due to its hydrophobic benzoyl group. It exhibits properties typical of both amides and ketones, making it a versatile intermediate in organic synthesis. The presence of the benzoyl group enhances its reactivity, allowing it to participate in various chemical reactions, including acylation and nucleophilic substitutions. Additionally, 2-Piperidinone, 1-benzoyl- may have applications in pharmaceuticals and agrochemicals, serving as a building block for the synthesis of more complex molecules. As with many organic compounds, handling should be done with care, following appropriate safety protocols to mitigate any potential health risks associated with exposure.

<p>1-Benzoylpiperidin-2-one is a cyclic amide that contains an iminium group. It is synthesized in the presence of phenolic and yields two isomers, with one being more stable than the other. 1-Benzoylpiperidin-2-one has been shown to inhibit nicotine metabolism by inhibiting cytochrome P450 enzymes. Mechanistically, 1-benzoylpiperidin-2-one binds to the heme moiety at the active site of the enzyme and acts as a reversible inhibitor. The nitrogen atom of 1-benzoylpiperidin-2-one binds to the methylene carbon of heme b, leading to inhibition of microsomal enzymes such as phenol hydroxylase and deuterium incorporation into piperidine metabolites.</p>

CAS 4252-56-6

2-Piperidinone, 1-benzoyl-

1-Benzoylpiperidin-2-one

Ref: 3D-EAA25256