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CAS 426253-04-5

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Razupenem

Description:
As of my last update in October 2023, "Razupenem" is a chemical compound classified as a beta-lactam antibiotic, specifically a penem. It is designed to combat bacterial infections by inhibiting cell wall synthesis in susceptible bacteria. The compound is characterized by its broad-spectrum activity against various Gram-positive and Gram-negative bacteria, making it a valuable option in treating resistant infections. Razupenem is typically administered parenterally and is known for its stability against certain beta-lactamases, enzymes produced by bacteria that confer resistance to other antibiotics. Its pharmacokinetic properties include good tissue penetration and a relatively short half-life, necessitating careful dosing to maintain effective therapeutic levels. As with many antibiotics, potential side effects may include allergic reactions, gastrointestinal disturbances, and effects on the microbiome. Ongoing research continues to evaluate its efficacy and safety profile in clinical settings, particularly in the context of rising antibiotic resistance. Always consult current scientific literature or databases for the most up-to-date information regarding specific compounds.
Formula:C18H21N3O4S2
InChI:InChI=1S/C18H21N3O4S2/c1-7-4-10(5-19-7)11-6-26-18(20-11)27-15-8(2)13-12(9(3)22)16(23)21(13)14(15)17(24)25/h4,6-9,12-13,19,22H,5H2,1-3H3,(H,24,25)/t7-,8+,9+,12+,13+/m0/s1
InChI key:InChIKey=XFGOMLIRJYURLQ-GOKYHWASSA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@@]([C@@H](C)O)(C2=O)[H])([C@@H](C)C1SC3=NC(=CS3)C4=C[C@H](C)NC4)[H]
Synonyms:
  • Razupenem
  • (4R,5S,6S)-3-[[4-[(5S)-2,5-Dihydro-5-methyl-1H-pyrrol-3-yl]-2-thiazolyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • SMP 601
  • SM 216601
  • 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[4-[(5S)-2,5-dihydro-5-methyl-1H-pyrrol-3-yl]-2-thiazolyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-
  • PTZ-601
  • PTZ 601
  • (4R,5S,6S)-6-((R)-1-Hydroxyethyl)-4-methyl-3-((4-((S)-5-methyl-2,5-dihydro-1H-pyrrol-3-yl)thia
  • PZ 601
  • PTZ601
  • (4R,5S,6S)-6-((R)-1-Hydroxyethyl)-4-methyl-3-((4-((S)-5-methyl-2,5-dihydro-1H-pyrrol-3-yl)thiazol-2-yl)thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic a
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Found 3 products.
  • Razupenem
    Targetmol
    + Info

    Razupenem

    CAS:
    <p>Razupenem (SMP-601, PTZ601), a broad-spectrum injectable carbapenem, counters antibiotic-resistant bacteria.</p>
    Formula:C18H21N3O4S2
    Color and Shape:Solid
    Molecular weight:407.51

    Ref: TM-T34270

  • Razupenem
    TRC
    + Info

    Razupenem

    CAS:
    Formula:C18H21N3O4S2
    Color and Shape:Neat

    Ref: TR-R145690

    10mg
    8,233.00€
  • (4R,5S,6S)-3-[[4-[(5S)-2,5-Dihydro-5-methyl-1H-pyrrol-3-yl]-2-thiazolyl]thio]-6-[(1R)-1-hydroxyeth…
    Biosynth
    + Info

    (4R,5S,6S)-3-[[4-[(5S)-2,5-Dihydro-5-methyl-1H-pyrrol-3-yl]-2-thiazolyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3. 2.0]hept-2-ene-2-carboxylicacid

    CAS:
    <p>Acyl-CoA thiolase (ACOT) is a bacterial enzyme that catalyzes the reaction of fatty acyl-CoA with CoA to form CoA esters and free fatty acids. The ACOT gene has been identified as an important virulence factor in Staphylococcus aureus isolates. Researchers have demonstrated that ACOT inhibitors can be used to treat bacterial infections by inhibiting the growth of bacteria and preventing them from forming biofilms, which are protective colonies of bacteria that adhere to surfaces and release substances harmful to the host. Gatifloxacin is an example of an ACOT inhibitor that has been shown to be active against methicillin-resistant Staphylococcus aureus (MRSA) and P. aeruginosa, although it is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.</p>
    Formula:C18H21N3O4S2
    Purity:Min. 95%
    Molecular weight:407.51 g/mol

    Ref: 3D-FD152101

    1mg
    2,746.00€