CAS 427-00-9

Desomorphine

Description:

Desomorphine, with the CAS number 427-00-9, is a potent opioid analgesic that is structurally related to morphine. It is known for its rapid onset of action and strong analgesic properties, making it effective for pain relief. Desomorphine is characterized by its high lipophilicity, which contributes to its ability to cross the blood-brain barrier quickly, leading to intense effects. However, it is also associated with a high potential for abuse and addiction. The substance has a relatively short duration of action, which can lead to repeated dosing and increased risk of dependence. Additionally, desomorphine has been linked to severe side effects, including tissue damage and necrosis, particularly when used illicitly in the form of "krokodil," a street drug that is often synthesized from codeine. Due to its potential for harm and abuse, desomorphine is classified as a controlled substance in many jurisdictions, and its medical use is limited.

Formula: C₁₇H₂₁NO₂

InChI: InChI=1S/C17H21NO2/c1-18-8-7-17-11-3-2-4-14(17)20-16-13(19)6-5-10(15(16)17)9-12(11)18/h5-6,11-12,14,19H,2-4,7-9H2,1H3/t11-,12+,14-,17+/m0/s1

InChI key: InChIKey=LNNWVNGFPYWNQE-GMIGKAJZSA-N

SMILES: OC1=C2C=3[C@@]45[C@]([C@@](CC3C=C1)(N(C)CC4)[H])(CCC[C@@]5(O2)[H])[H]

Synonyms:

• (5Alpha)-17-Methyl-4,5-Epoxymorphinan-3-Ol
• (5α)-4,5-Epoxy-17-methylmorphinan-3-ol
• 4,5-Epoxy-3-hydroxy-N-methylmorphinan
• 6-Deoxy-7,8-dihydromorphine
• 7,8-Dihydro-6-Deoxymorphine
• Deoxydihydromorphine D
• Dihydrodeoxymorphine
• Dihydrodesoxymorphine D
• Dihydroepoxymorphine
• Morphinan-3-ol, 4,5-epoxy-17-methyl-, (5α)-
• Morphine D, deoxydihydro-
• Morphine, 6-deoxy-7,8-dihydro-
• Permonid

Desomorphine, 1mg/ml in Acetonitrile

Controlled Product

CAS: 427-00-9

Color and Shape: Single Solution

Ref: LP-M-1415-FB-1LA

Desomorphine (Dihydrodesoxymorphine; Krokodil) 1.0 mg/ml in Acetonitrile

Controlled Product

CAS: 427-00-9

Color and Shape: Single Solution

Ref: 61-AMP0037.21-11

Desomorphine

Controlled Product

CAS: 427-00-9

Color and Shape: Neat

Ref: LP-M-1415-FB-10

Desomorphine (1.0 mg/mL in Acetonitrile)

Controlled Product

CAS: 427-00-9

Formula: C₁₇H₂₁NO₂

Color and Shape: Single Solution

Molecular weight: 271.35

Ref: TR-KIT0980

Desomorphine

Controlled Product

CAS: 427-00-9

Applications Analgesic (narcotic). Controlled substance (opium derivative).
References Zhao, M., et al.: Bioorg. Med. Chem., 15, 2815 (2007), Zhao, M., et al.: Eur. J. Med. Chem., 43, 1048 (2008), Roy, K., et al.: Eur. J. Med. Chem., 44, 2913 (2009),

Formula: C₁₇H₂₁NO₂

Color and Shape: Neat

Molecular weight: 271.35

Ref: TR-D296900