CAS 4277-89-8

Myristoylcholine chloride

Description:

Myristoylcholine chloride, with the CAS number 4277-89-8, is a quaternary ammonium compound that serves as a synthetic derivative of choline. It is characterized by its myristoyl (tetradecanoyl) fatty acid chain, which contributes to its amphiphilic properties, allowing it to interact with both hydrophilic and hydrophobic environments. This compound typically appears as a white to off-white solid or powder and is soluble in water, making it suitable for various applications in biochemistry and pharmacology. Myristoylcholine chloride is often utilized in research settings, particularly in studies related to cell membrane dynamics and signaling pathways, due to its ability to mimic the action of acetylcholine, a key neurotransmitter. Additionally, its quaternary ammonium structure imparts cationic characteristics, which can enhance its interaction with biological membranes. Safety data should be consulted for handling and usage, as with all chemical substances, to ensure proper precautions are taken.

Formula: C₁₉H₄₀NO₂·Cl

InChI: InChI=1S/C19H40NO2.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-19(21)22-18-17-20(2,3)4;/h5-18H2,1-4H3;1H/q+1;/p-1

InChI key: InChIKey=CNJMYRYCYNAIOF-UHFFFAOYSA-M

SMILES: C(CCCCCCCCCCCCC)(OCC[N+](C)(C)C)=O.[Cl-]

Synonyms:

• Myristoyl choline
• Ethanaminium, N,N,N-trimethyl-2-[(1-oxotetradecyl)oxy]-, chloride (1:1)
• Myristic acid, ester with choline chloride
• Ethanaminium, N,N,N-trimethyl-2-[(1-oxotetradecyl)oxy]-, chloride
• Choline, chloride, myristate

N,N,N-Trimethyl-2-(tetradecanoyloxy)ethanaminium chloride

CAS: 4277-89-8

Formula: C₁₉H₄₀ClNO₂

Purity: 90%

Color and Shape: Solid

Molecular weight: 349.9794

Ref: IN-DA003S70

Myristoylcholine chloride

CAS: 4277-89-8

Myristoylcholine chloride

Purity: 98%

Molecular weight: 349.98g/mol

Ref: 54-OR1007334

Myristoylcholine chloride

CAS: 4277-89-8

Molecular weight: 349.98

Ref: 7W-GL2911

Myristoylcholine Chloride

Controlled Product

CAS: 4277-89-8

Formula: C₁₉H₄₀NO₂·Cl

Color and Shape: Neat

Molecular weight: 349.98

Ref: TR-M885000

Myristoylcholine chloride

CAS: 4277-89-8

Myristoylcholine chloride is a monolayer-forming cationic surfactant that can be used as an antimicrobial agent. It forms stable complexes with fatty acids, which are non-polymeric and hydrophobic. This product has been shown to have hemolytic activity, and also exhibits antibacterial properties against gram-positive bacteria, such as Streptococcus pneumoniae and Staphylococcus aureus. Myristoylcholine chloride is not active against gram-negative bacteria, such as Pseudomonas aeruginosa.
Myristoylcholine chloride forms stable complexes with pentacosanoic acid (PCA) when mixed in solution. The chemical structure of PCA is shown below:
CH(CH)COOH
The enzyme hydrolysis of PCA by choline esterases results in the formation of choline and pentacosanoic acid.

Formula: C₁₉H₄₀ClNO₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 349.98 g/mol

Ref: 3D-FM26114