CAS 42771-81-3

Diethyl 2-[2-fluro-4-biphenyl-4-yl]-2 methylmalonate

Description:

Diethyl 2-[2-fluoro-4-biphenyl-4-yl]-2-methylmalonate, identified by its CAS number 42771-81-3, is an organic compound characterized by its complex structure, which includes a diethyl malonate moiety and a biphenyl group substituted with a fluorine atom. This compound typically exhibits properties associated with esters, such as being a colorless to pale yellow liquid or solid, depending on its purity and specific conditions. It is likely to be soluble in organic solvents like ethanol and dichloromethane, while being less soluble in water due to its hydrophobic biphenyl structure. The presence of the fluorine atom can influence its reactivity and polarity, potentially enhancing its biological activity or stability. Diethyl 2-[2-fluoro-4-biphenyl-4-yl]-2-methylmalonate may be of interest in medicinal chemistry and material science, particularly in the development of pharmaceuticals or as an intermediate in organic synthesis. However, specific safety and handling guidelines should be followed, as with any chemical substance.

Flurbiprofen Impurity 1

CAS: 42771-81-3

Formula: C₂₀H₂₁FO₄

Color and Shape: Colorless Liquid

Molecular weight: 344.38

Ref: 4Z-F-0817

2-(2-Fluoro[1,1'-biphenyl]-4-yl)-2,3-dimethylbutanedioic Acid Dimethyl Ester

Controlled Product

CAS: 42771-81-3

Applications 2-(2-Fluoro[1,1'-biphenyl]-4-yl)-2,3-dimethylbutanedioic Acid Dimethyl Ester is an intermediate in the synthesis of 2-(2-Fluoro[1,1'-biphenyl]-4-yl)-2,3-dimethylbutanedioic acid which is an impurity of Flurbiprofen (F598700), an anti-inflammatory used as an analgesic. Flurbiprofen impurity B.
References Beaulieu, N., et al.: Drug Develop. Industrial Pharmacy, 17, 1843 (1991);

Formula: C₁₅H₁₆ClN₃O₄·CH₄O₃S

Color and Shape: Neat

Molecular weight: 433.864

Ref: TR-F588768

Flurbiprofen Impurity 1

CAS: 42771-81-3

Formula: C₂₀H₂₁FO₄

Molecular weight: 344.38

Ref: ST-EA-CP-F21008