CAS 42794-76-3

Midodrine

Description:

Midodrine is a synthetic medication primarily used as a vasopressor to treat orthostatic hypotension, a condition characterized by abnormally low blood pressure upon standing. It functions as a prodrug, converting into its active form, desglymidodrine, which stimulates alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. Midodrine is typically administered orally and is known for its relatively long duration of action. Its chemical structure includes a phenyl ring and an amine group, contributing to its pharmacological properties. Common side effects may include supine hypertension, piloerection, and urinary retention. Due to its mechanism of action, midodrine is contraindicated in patients with severe heart disease or those with urinary retention issues. Monitoring of blood pressure is essential during treatment to avoid complications. Overall, midodrine serves as an important therapeutic option for managing specific forms of hypotension, enhancing patient quality of life when used appropriately.

Formula: C₁₂H₁₈N₂O₄

InChI: InChI=1/C12H18N2O4/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16)

InChI key: InChIKey=PTKSEFOSCHHMPD-UHFFFAOYSA-N

SMILES: C(CNC(CN)=O)(O)C1=C(OC)C=CC(OC)=C1

Synonyms:

• 1-(2′,5′-Dimethoxyphenyl)-2-glycinamidoethanol
• Acetamide, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-
• (±)-Midodrine
• Midodrine
• 2-Amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide
• Acetamide, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]- (9CI)
• 2-Amino-N-(2,5-dimethoxy-β-hydroxyphenethyl)acetamide
• MIDODRINE USP/EP/BP

Midodrine

CAS: 42794-76-3

Formula: C₁₂H₁₈N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 254.2823

Ref: IN-DA00C0OH

Midodrine

CAS: 42794-76-3

Midodrine

Purity: ≥98%

Molecular weight: 254.28g/mol

Ref: 54-BUP10477

Midodrine

CAS: 42794-76-3

Midodrine ((±)-Midodrin), an adrenergic alpha-1 agonist, belongs to the class of medications known as vasopressors.

Formula: C₁₂H₁₈N₂O₄

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 254.28

Ref: TM-T22369

Midodrine

Controlled Product

CAS: 42794-76-3

2-Amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-acetamide is a drug that has been used to treat a variety of diseases and conditions. It is an alpha adrenergic agonist that works by stimulating the alpha receptors in the body, which increase blood pressure and improve blood flow. This drug also has significant effects on energy metabolism, including the production of ATP. 2-Amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-acetamide is used to treat patients with congestive heart failure who are taking low doses of midodrine hydrochloride or nonsteroidal antiinflammatory drugs.

Formula: C₁₂H₁₈N₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 254.28 g/mol

Ref: 3D-FA157966