CAS 42835-89-2

6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline

Description:

6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline is a bicyclic organic compound characterized by its fused ring structure, which includes a quinoline moiety. The presence of a fluorine atom at the 6-position and a methyl group at the 2-position contributes to its unique chemical properties. This compound typically exhibits a pale yellow to light brown appearance and is soluble in organic solvents, reflecting its hydrophobic nature. It is known for its potential biological activity, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. The tetrahydroquinoline framework is often associated with various biological activities, including antimicrobial and anticancer properties. Additionally, the compound's reactivity can be influenced by the presence of the fluorine atom, which can enhance lipophilicity and alter the electronic properties of the molecule. As with many organic compounds, safety and handling precautions should be observed, as it may pose health risks if not managed properly.

Formula: C₁₀H₁₂FN

InChI: InChI=1/C10H12FN/c1-7-2-3-8-6-9(11)4-5-10(8)12-7/h4-7,12H,2-3H2,1H3

InChI key: InChIKey=BDCCXYVTXRUGAN-UHFFFAOYSA-N

SMILES: FC=1C=C2C(NC(C)CC2)=CC1

Synonyms:

• 1,2,3,4-Tetrahydro-6-fluoro-2-methylquinoline
• 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline
• Quinoline, 6-fluoro-1,2,3,4-tetrahydro-2-methyl-
• 6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline
• 2-Methyl-6-fluoro-1,2,3,4-tetrahydroquinoline
• 6-fluoro-tetrahydro-quinaldine
• 6-FLUORO-2-METHYL-1,2,3,4-TETRAHYDROQUINOLINE 99
• 6-Fluoro-1
• 1,2,3,4-Tetrahydro-2-methyl-6-fluoroquinoline
• 6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline 99%
• 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline,98%

6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline

CAS: 42835-89-2

Formula: C₁₀H₁₂FN

Purity: 98%

Color and Shape: Solid

Molecular weight: 165.2074

Ref: IN-DA00I89G

6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline

CAS: 42835-89-2

6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline

Purity: 98%

Molecular weight: 165.21g/mol

Ref: 54-PC4146

6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline

Controlled Product

CAS: 42835-89-2

Applications Intermediate in the production of anti-cancer quinoline derivatives and antibacterial agents
References Zhao, H., et al.: Bioorg. Med. Chem. Lett., 12, 3105 (2002),

Formula: C₁₀H₁₂FN

Color and Shape: Neat

Molecular weight: 165.21

Ref: TR-F593800

6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline

CAS: 42835-89-2

6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline is an organocatalytic fluorine compound that has been investigated as a fluoroquinolone antibiotic. It is an enantiopure compound and has been shown to be effective in the treatment of bacterial infections. 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline inhibits bacterial growth by binding to DNA gyrase and topoisomerase IV. 6FLMQ is a chiral molecule with two possible configurations (R or S), which can be determined from x-ray crystallography. The S configuration is more potent than the R configuration. 6FLMQ also binds with chloride ions to form a cationic complex that can be used for antibacterial activity against Gram negative bacteria such as Escherichia coli and Pseudomonas aeruginosa.
6FLMQ has

Formula: C₁₀H₁₂FN

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 165.21 g/mol

Ref: 3D-FF23361

6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline

CAS: 42835-89-2

Formula: C₁₀H₁₂FN

Purity: 98%

Color and Shape: Solid, Crystalline

Molecular weight: 165.211

Ref: 10-F067506