CAS 42895-58-9

(2R,5R,6S,10R)-2,17-dihydroxy-20-oxo-9,19-didehydro-5,6,7,8,9,10,15-octahydro-20:5,10-dicycloretinal

Description:

The chemical substance known as (2R,5R,6S,10R)-2,17-dihydroxy-20-oxo-9,19-didehydro-5,6,7,8,9,10,15-octahydro-20:5,10-dicycloretinal, with the CAS number 42895-58-9, is a complex organic compound characterized by its specific stereochemistry and functional groups. It features multiple hydroxyl (-OH) groups, indicating its potential for hydrogen bonding and solubility in polar solvents. The presence of a ketone group (20-oxo) suggests reactivity typical of carbonyl compounds, which can participate in various chemical reactions, including nucleophilic additions. The compound's structure includes multiple rings and a didehydro configuration, which may influence its biological activity and interaction with other molecules. This substance is likely to be of interest in fields such as biochemistry and pharmacology, particularly in studies related to retinal compounds or similar organic molecules. Its stereochemical configuration may also play a crucial role in its biological function and interaction with receptors or enzymes.

Formula: C₂₀H₂₈O₄

InChI: InChI=1/C20H28O4/c1-13-4-7-16-19(2,10-8-17(22)20(16,3)12-21)15(13)6-5-14-9-11-24-18(14)23/h5-6,9,15-17,21-22H,1,4,7-8,10-12H2,2-3H3/b6-5+/t15-,16+,17-,19+,20+/m1/s1

Synonyms:

• 2(5H)-furanone, 3-[(E)-2-[(1R,4aS,5R,6R,8aR)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethenyl]-
• 3-{(E)-2-[(1R,4aS,5R,6R,8aR)-6-Hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl]vinyl}furan-2(5H)-one

14-Deoxy-11,12-didehydroandrographolide

CAS: 42895-58-9

Formula: C₂₀H₂₈O₄

Purity: %

Molecular weight: 332.4339

Ref: IN-DA00BY3C

14-Deoxy-11,12-didehydroandrographolide

CAS: 42895-58-9

Formula: C₂₀H₂₈O₄

Molecular weight: 332.44

Ref: 7W-GY4520

14-Deoxy-11,12-didehydroandrographolide

CAS: 42895-58-9

14-Deoxy-11,12-didehydroandrographolide

Purity: ≥98%

Molecular weight: 332.43g/mol

Ref: 54-BUP08761

14-Deoxy-11,12-didehydroandrographolide

CAS: 42895-58-9

Formula: C₂₀H₂₈O₄

Purity: 95%~99%

Molecular weight: 332.44

Ref: BP-SBP02104

14-Deoxy-11,12-didehydroandrographolide

CAS: 42895-58-9

14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.

Formula: C₂₀H₂₈O₄

Purity: 99.13% - 99.93%

Color and Shape: Solid

Molecular weight: 332.43

Ref: TM-TQ0185

14-deoxy 11,14-didehydroandrographolide

CAS: 42895-58-9

Lactone

Formula: C₂₀H₂₈O₄

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 332.44

Ref: 5G-89631

14-Deoxy-11,12-didehydroandrographolide

CAS: 42895-58-9

14-Deoxy-11,12-didehydroandrographolide is a bioactive compound that belongs to the group of andrographolides. It has been shown to have significant cytotoxicity against HL-60 cells and induces apoptosis in these cells. 14-Deoxy-11,12-didehydroandrographolide also has antiinflammatory activity and binding affinity for the response element (ARE), which is a DNA sequence that regulates gene expression. This compound may be useful for treating bowel diseases such as ulcerative colitis or Crohn's disease because it inhibits inflammatory responses in these conditions. 14-Deoxy-11,12-didehydroandrographolide can also bind to mitochondrial membranes, preventing them from breaking down and leading to cell death. This compound can form a complex with the dna strand, inhibiting its synthesis.

Formula: C₂₀H₂₈O₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 332.43 g/mol

Ref: 3D-FD42724