CAS 429-41-4

Tetrabutylammonium fluoride

Description:

Tetrabutylammonium fluoride (TBAF) is an organic compound with the formula (C4H9)4NF. It is a quaternary ammonium salt, characterized by its four butyl groups attached to a nitrogen atom, which is also bonded to a fluoride ion. TBAF is typically encountered as a white crystalline solid or a colorless solution in polar solvents. It is known for its strong basicity and is often used as a fluoride source in organic synthesis, particularly in reactions involving the deprotection of silyl ethers. TBAF is soluble in polar aprotic solvents like dimethyl sulfoxide (DMSO) and acetonitrile, but it is less soluble in nonpolar solvents. The compound is hygroscopic, meaning it can absorb moisture from the air, which can affect its stability and reactivity. Safety precautions are necessary when handling TBAF, as it can be corrosive and toxic upon contact with skin or if inhaled. Overall, TBAF is a valuable reagent in synthetic organic chemistry, particularly in the preparation of fluorinated compounds.

Formula: C₁₆H₃₆N·F

InChI: InChI=1S/C16H36N.FH/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;/h5-16H2,1-4H3;1H/q+1;/p-1

InChI key: InChIKey=FPGGTKZVZWFYPV-UHFFFAOYSA-M

SMILES: [N+](CCCC)(CCCC)(CCCC)CCCC.[F-]

Synonyms:

• 1-Butanaminium, N,N,N-tributyl-, fluoride (1:1)
• Ammonium, tetrabutyl-, fluoride
• Fluorure de tetrabutylammonium
• Fluoruro De Tetrabutilamonio
• Tbaf
• Tetra-n-butylammonium fluoride
• Tetrabutylammonium Fluoride
• Tetrabutylammoniumfluorid
• Tetranbutylammoniumfluoride
• lithiumtrisamylborohydride
• ls-selectride
• tetrabutyl ammonium fluoride
• tetra butyl ammonium fluoride
• N,N,N-tributylbutan-1-aminium fluoride trihydrate
• ls-selectride(r)
• lithium trisiamylborohydride
• lithium triisoamylborohydride

Tetrabutylammonium Fluoride (70-75% in Water)

CAS: 429-41-4

Formula: C₁₆H₃₆FN

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 261.47

Ref: 3B-T1339

Tetrabutylammonium Fluoride (ca. 1mol/L in Tetrahydrofuran)

CAS: 429-41-4

Formula: C₁₆H₃₆FN

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 261.47

Ref: 3B-T1338

Tetrabutylammonium Fluoride (ca. 1mol/L in Tetrahydrofuran) [for Catalyst of silylation and cleavage of silyl ether]

CAS: 429-41-4

Formula: C₁₆H₃₆FN

Color and Shape: Colorless to Yellow clear liquid

Molecular weight: 261.47

Ref: 3B-T1125

Tetra-n-butylammonium fluoride, 75% w/w aq. soln.

CAS: 429-41-4

Tetrabutylammonium Fluoride is a reactant used for the synthesis of multiple compounds, including conjugated dienoic acid esters, oligoribonucleotides with phosphonate-modified linkages, and triple monoamine reuptake inhibitors, among others. It has proven useful in studying cancer, diabetes, and ne

Formula: C₁₆H₃₆FN

Purity: 75%

Color and Shape: Clear colorless to yellow, Viscous liquid

Molecular weight: 261.47

Ref: 02-B21261

Tetra-n-butylammonium fluoride, 1M soln. in THF

CAS: 429-41-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₆H₃₆FN

Color and Shape: Clear colorless to brown, Liquid

Molecular weight: 261.47

Ref: 02-A10588

Tetrakis(but-1-yl)ammonium fluoride 1.0M solution in THF

CAS: 429-41-4

Tetrakis(but-1-yl)ammonium fluoride 1.0M solution in THF

Formula: ·F·N(C₄H₉)₄

Purity: ≥95%

Color and Shape: Pale yellow Liquid

Molecular weight: 261.46214

Ref: 54-PC1945

Tetrabutylammonium fluoride, 1M in THF

CAS: 429-41-4

Formula: CH₃(CH₂)₃NF

Color and Shape: Colourless to light yellow or light brown liquid

Molecular weight: 261.46

Ref: 7W-GX5205

Tetra(but-1-yl)ammonium fluoride, 72% aqueous solution

CAS: 429-41-4

Tetra(but-1-yl)ammonium fluoride, 72% aqueous solution

Formula: ·F·N(C₄H₉)₄

Purity: ≥95%

Color and Shape: Liquid

Ref: 54-PC99472

Tetrabutylammonium Fluoride (1.0 M in THF)

Controlled Product

CAS: 429-41-4

Formula: C₁₆H₃₆FN

Color and Shape: Single Solution

Molecular weight: 261.46

Ref: TR-T291235

Tetra(but-1-yl)ammonium fluoride, 75% aqueous solution

CAS: 429-41-4

Tetra(but-1-yl)ammonium fluoride, 75% aqueous solution

Formula: ·F·N(C₄H₉)₄

Purity: ≥95%

Color and Shape: Liquid

Molecular weight: 261.46214

Ref: 54-PC51166

Tetrabutylammonium fluoride - 1.0M in THF

CAS: 429-41-4

Tetrabutylammonium fluoride-1.0M in THF is a solution of tetrabutylammonium fluoride in tetrahydrofuran. The compound is soluble in water and THF with solubility increasing with temperature. Tetrabutylammonium fluoride has been shown to be an effective inhibitor of the enzyme 4-hydroxycinnamic acid transaminase, which is involved in the metabolism of catecholamines. This property may be due to the ability of tetrabutylammonium fluoride to bind to the active site metal ion, copper, that participates in this reaction. Tetrabutylammonium fluoride can also inhibit other enzymes by binding to metal ions at their active sites, such as pyridoxal phosphate and hydroxyl groups.

Formula: C₁₆H₃₆FN

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 261.46 g/mol

Ref: 3D-FT63325

Tetrabutylammonium fluoride, 1M in THF

CAS: 429-41-4

Tetrabutylammonium fluoride, 1M in THF

Formula: (C₄H₉)₄NF

Color and Shape: colorless to pale-yellow liq.

Molecular weight: 261.46

Ref: 08-02-5012

Tetrabutylammonium fluoride - 75 wt. % in H2O

CAS: 429-41-4

Tetrabutylammonium fluoride is a strong base which reacts with the hydroxyl group of a carboxylic acid to form a salt and hydrogen fluoride. The nucleophilic nature of tetrabutylammonium and its high polarity make it an excellent catalyst for this reaction. Tetrabutylammonium fluoride has been shown to react with sodium salts in nonpolar solvents, such as benzene or toluene, to form quinoline derivatives. It also has been used in the synthesis of x-ray crystal structures of organic molecules by reacting with carbonyl groups, such as acetaldehyde. Tetrabutylammonium fluoride can interact chemically with other compounds, such as hydrogen bond formation with amines or reactions with amides.

Formula: C₁₆H₃₆FN

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 261.46 g/mol

Ref: 3D-FT76108

Tetrabutylammonium Fluoride (TBAF) 1M Soln. in THF

CAS: 429-41-4

Formula: C₁₆H₃₆FN

Color and Shape: Clear, Pale yellow to brown, Liquid

Molecular weight: 261.47

Ref: SR-30315